Comprehensive biotechnology Vol. 2/ (Record no. 180138)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 00387nam a2200121Ia 4500 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CUS |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 660.6 |
| Item number | MOO/C |
| 245 #0 - TITLE STATEMENT | |
| Title | Comprehensive biotechnology Vol. 2/ |
| Sub title | principles and practices in industry agriculture medicine and the environment |
| Statement of responsibility, etc. | Moo-Young,Murray |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication, distribution, etc. | Amsterdam: |
| Name of publisher, distributor, etc. | Elsevier, |
| Date of publication, distribution, etc. | 2011. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 690 |
| 505 ## - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 2.01. Introduction<br/><br/>2.02. Bioengineering at the Interface between Science and Society<br/><br/>Glossary<br/><br/>2.02.1. Introduction<br/><br/>2.02.2. The Impact of Science and Technology on Society<br/><br/>2.02.3. Roots and Development of Evolutionary Biology and of Genetics<br/><br/>2.02.4. Genetic Engineering as a Source of Genetic Variants<br/><br/>2.02.5. Molecular Mechanisms and Natural Strategies of Spontaneous Genetic Variation<br/><br/>2.02.6. High Similarity between Natural Biological Evolution and the Contribution of Genetic Engineering to Biological Evolution<br/><br/>2.02.7. Risk Evaluation of Evolutionary Processes<br/><br/>2.02.8. Prospects of Bioengineering<br/><br/>2.02.9. Public Perception of Genetics, Biological Evolution, and Bioengineering<br/><br/>2.02.10. Call for Sustainability of Cultural Developments<br/><br/>2.03. Cellular Systems<br/><br/>Glossary<br/><br/>2.03.1. Introduction<br/><br/>2.03.2. Bacteria<br/><br/>2.03.3. Fungi<br/><br/>2.03.4. Plant Cells<br/><br/>2.03.5. Animal Cells<br/><br/>2.03.6. Human Stem Cells<br/><br/>2.03.7. Artificial Cells<br/><br/>2.04. Cell Growth Dynamics<br/><br/>Glossary<br/><br/>2.04.1. Introduction<br/><br/>2.04.2. Models of Cells in Submerged Culture<br/><br/>2.04.3. Models of Cells in Multiphase Fermentor<br/><br/>2.05. Reaction Kinetics and Stoichiometry<br/><br/>Glossary<br/><br/>2.05.1. Introduction<br/><br/>2.05.2. Enzyme Kinetics<br/><br/>2.05.3. Factors Affecting Reaction Kinetics<br/><br/>2.05.4. Biochemical Reaction Rate Related to Cellular Systems<br/><br/>2.05.5. Stoichiometry<br/><br/>2.06. Bioreactor Fluid Dynamics<br/><br/>Glossary<br/><br/>2.06.1. Introduction<br/><br/>2.06.2. Mixing<br/><br/>2.06.3. Residence Time Measurements of the Gas Flow<br/><br/>2.06.4. Flow around Single Bubbles<br/><br/>2.06.5. Flow around Impeller Blades<br/><br/>2.06.6. Oxygen Mass Transfer<br/><br/>2.06.7. Flow Patterns in Stirred Tanks<br/><br/>2.06.8. Flow Patterns in Bubble Columns<br/><br/>2.06.9. Take-Home Messages<br/><br/>2.07. Mixing in Bioreactor Vessels<br/><br/>Glossary<br/><br/>2.07.1. Introduction<br/><br/>2.07.2. Characterization of Mixing<br/><br/>2.07.3. Mixing Models<br/><br/>2.07.4. Experimental Verification<br/><br/>2.07.5. The Airlift<br/><br/>2.07.6. Comparison of the Reactor Types<br/><br/>2.07.7. Gas-Phase Mixing<br/><br/>2.07.8. The Meaning of Mixing<br/><br/>2.07.9. Conclusions<br/><br/>2.08. Genetic Engineering<br/><br/>Glossary<br/><br/>2.08.1. Introduction to Genetic Engineering<br/><br/>2.08.2. Molecular Cloning and Recombinant DNA Technology<br/><br/>2.08.3. Molecular Manipulations<br/><br/>2.08.4. Cellular Manipulations<br/><br/>2.09. Bio-Feedstocks<br/><br/>Glossary<br/><br/>2.09.1. Common Feedstocks<br/><br/>2.09.2. Lignocellulose<br/><br/>2.09.3. Use of Perennial Grasses<br/><br/>2.10. Substrate Hydrolysis<br/><br/>Glossary<br/><br/>2.10.1. Introduction<br/><br/>2.10.2. Substrate for Hydrolysis<br/><br/>2.10.3. Physical Methods for Hydrolysis<br/><br/>2.10.4. Chemical Methods for Hydrolysis<br/><br/>2.10.5. Enzymatic Hydrolysis<br/><br/>2.10.6. Concluding Remarks<br/><br/>2.11. Medium Formulation and Development<br/><br/>Glossary<br/><br/>2.11.1. Introduction<br/><br/>2.11.2. Medium Formulation<br/><br/>2.11.3. Medium Optimization<br/><br/>2.11.4. Genetic Algorithms<br/><br/>2.11.5. Platforms for Medium Development<br/><br/>2.12. Sterilization in Biotechnology<br/><br/>Nomenclature<br/><br/>2.12.1. Introduction<br/><br/>2.12.2. Sterilization of Gases<br/><br/>2.12.3. Sterilization of Liquids<br/><br/>2.12.4. Sterilization of Small Equipment<br/><br/>2.12.5. Sterilization of Large Equipment<br/><br/>2.12.6. Validation of Sterilization<br/><br/>2.12.7. Conclusions<br/><br/>2.13. Inoculum Preparation<br/><br/>Glossary<br/><br/>Acknowledgments<br/><br/>2.13.1. Introduction<br/><br/>2.13.2. Criteria for Inoculum Preparation for Fermentation Process<br/><br/>2.13.3. Inoculum Development Process for Fermentation<br/><br/>2.13.4. Monitoring Inoculum Development<br/><br/>2.13.5. Transfer of Inoculum to the Fermentor Vessel or Scale-Up Process<br/><br/>2.13.6. Inoculum Preparation for Antimicrobial Susceptibility Testing<br/><br/>2.13.7. Measurement of Bacteria and Inoculum Preparation<br/><br/>2.13.8. Inoculum Preparation for Viral Cultures<br/><br/>2.13.9. Inoculum Preparation for Mammalian Cell Culture<br/><br/>2.13.10. Inoculum for Immunization<br/><br/>2.13.11. Conclusion<br/><br/>2.14. Bioreactor Engineering<br/><br/>Glossary<br/><br/>Acknowledgment<br/><br/>2.14.1. Introduction<br/><br/>2.14.2. Design and Types of Bioreactors<br/><br/>2.14.3. Effects of Process Parameters on Biological Performances<br/><br/>2.14.4. Bioreactor Operation Strategy<br/><br/>2.14.5. Industrial Applications of Bioreactors<br/><br/>2.14.6. Trends in Bioreactor Engineering<br/><br/>2.15. Stirred Tank Bioreactors<br/><br/>Glossary<br/><br/>2.15.1. Introduction<br/><br/>2.15.2. Mass and Energy Balances<br/><br/>2.15.3. Kinetic Models<br/><br/>2.15.4. Case in Study: Xanthan Gum Production<br/><br/>2.16. Airlift Bioreactors<br/><br/>Glossary<br/><br/>2.16.1. Introduction<br/><br/>2.16.2. Reactor Configurations<br/><br/>2.16.3. Power Input<br/><br/>2.16.4. Gas–Liquid Hydrodynamics<br/><br/>2.16.5. Mass Transfer<br/><br/>2.16.6. Heat Transfer<br/><br/>2.16.7. Mixing<br/><br/>2.16.8. Applications<br/><br/>2.16.9. Conclusions<br/><br/>2.17. Shake-Flask Bioreactors<br/><br/>Glossary<br/><br/>2.17.1. Introduction<br/><br/>2.17.2. Specific Power Input in Shake Flasks<br/><br/>2.17.3. Out-of-Phase Phenomena in Shake Flasks<br/><br/>2.17.4. Maximum Energy Dissipation Rate in Shake Flasks<br/><br/>2.17.5. Gas/Liquid Mass Transfer in Shake Flasks<br/><br/>2.17.6. Baffled Shake Flasks<br/><br/>2.17.7. Use of Engineering Parameters for Scale-Up from Shake Flask to Stirred-Tank Reactor<br/><br/>2.17.8. Fed-Batch and Continuous Cultures in Shake Flasks<br/><br/>2.17.9. Online Measuring Techniques in Shake Flasks<br/><br/>2.18. Photobioreactors – Models of Photosynthesis and Related Effects<br/><br/>Glossary<br/><br/>2.18.1. Introduction<br/><br/>2.18.2. The P–I Curve<br/><br/>2.18.3. Mathematical Representation of Photosynthesis<br/><br/>2.18.4. Modeling and Interpretation of Irradiance<br/><br/>2.18.5. The Kinetic Model<br/><br/>2.18.6. Modeling Photoacclimation<br/><br/>2.18.7. Photosynthesis in the Bioreactor<br/><br/>2.18.8. Simulated Illumination–Darkness Cycles<br/><br/>2.18.9. Experimental Evaluation of Illumination–Darkness Cycles<br/><br/>2.18.10. Conclusions<br/><br/>2.19. Disposable Bioreactors<br/><br/>Glossary<br/><br/>2.19.1. Introduction<br/><br/>2.19.2. Types of Single-Use Bioreactors with Disposable Bags<br/><br/>2.19.3. Conclusions<br/><br/>2.20. Membrane Bioreactors<br/><br/>Glossary<br/><br/>2.20.1. Introduction<br/><br/>2.20.2. Basic Concepts in Membrane Bioreactors<br/><br/>2.20.3. Membrane Bioreactors for Production and Separation of Bioactive Molecules<br/><br/>2.20.4. Membrane Bioreactors for Bioartificial Organs and Engineered-Tissue Culture<br/><br/>2.20.5. Conclusions<br/><br/>2.21. Microbioreactors<br/><br/>Glossary<br/><br/>2.21.1. Introduction<br/><br/>2.21.2. Microfluidic Devices<br/><br/>2.21.3. Microbioreactors for Cell Culturing<br/><br/>2.21.4. Enzymatic Microreactors<br/><br/>2.21.5. Future Perspectives of Bioreactor Miniaturization<br/><br/>2.22. Biofilters<br/><br/>Glossary<br/><br/>2.22.1. Introduction<br/><br/>2.22.2. Types of Biofilters<br/><br/>2.22.3. Filter Media<br/><br/>2.22.4. Microorganisms<br/><br/>2.22.5. Factors Affecting BF Performance<br/><br/>2.22.6. Design<br/><br/>2.23. Enzyme Bioreactors<br/><br/>Glossary<br/><br/>2.23.1. Introduction<br/><br/>2.23.2. Forms of Enzymes Used in Enzyme Reactors<br/><br/>2.23.3. Enzyme Reactors<br/><br/>2.23.4. Design and Choice of Enzyme Reactors<br/><br/>2.23.5. Novel Enzyme Reactors<br/><br/>2.24. Immobilized Cell Bioreactors<br/><br/>Glossary<br/><br/>2.24.1. Introduction<br/><br/>2.24.2. Immobilization of Microbial Cells<br/><br/>2.24.3. Immobilized Cell Bioreactors: Configuration and Design Characteristics<br/><br/>2.24.4. Mass Transfer and Biokinetics in Immobilized Cell Bioreactors<br/><br/>2.24.5. Merits of Immobilized Cell Bioreactors<br/><br/>2.24.6. Potential Drawbacks<br/><br/>2.24.7. Concluding Remarks<br/><br/>2.25. Bioreactors for Solid-State Fermentation<br/><br/>Glossary<br/><br/>2.25.1. Introduction<br/><br/>2.25.2. Classification of SSF Bioreactors and Basic Principles of Operation<br/><br/>2.25.3. Tray Bioreactors<br/><br/>2.25.4. Packed-Bed Bioreactors<br/><br/>2.25.5. Rotating-Drum and Stirred-Drum Bioreactors<br/><br/>2.25.6. Forcefully Aerated Agitated Bioreactors<br/><br/>2.25.7. Challenges Related to Changes Provoked by Microbial Growth<br/><br/>2.25.8. Other Considerations<br/><br/>2.25.9. Conclusion<br/><br/>2.26. Bioreactors for Plant Cell Culture<br/><br/>Glossary<br/><br/>2.26.1. Introduction<br/><br/>2.26.2. General Aspects of Plant Cells<br/><br/>2.26.3. Various Types of Reactors for Plant Cell Culture<br/><br/>2.26.4. Operation of Plant Cell Reactors<br/><br/>2.26.5. Industrial Applications and Outlook for the Future<br/><br/>2.26.6. Summary<br/><br/>2.27. Bioreactors for Animal Cell Cultures<br/><br/>Glossary<br/><br/>2.27.1. Introduction<br/><br/>2.27.2. Bioreactor Design<br/><br/>2.27.3. Bioreactors for High Cell Density Cultures<br/><br/>2.27.4. Automation of Cell Processing toward Clinical Application<br/><br/>2.27.5. Concluding Remarks<br/><br/>2.28. Bioreactors for Tissue Engineering<br/><br/>Glossary<br/><br/>Acknowledgments<br/><br/>2.28.1. Introduction<br/><br/>2.28.2. Engineering Concepts in Tissue Mass Growth<br/><br/>2.28.3. Reactor Designs for Tissue Engineering<br/><br/>2.28.4. Noninvasive and Nondestructive Imaging Techniques to Monitor Bioreactor Tissue Cultures<br/><br/>2.28.5. Conclusions<br/><br/>2.29. Recombinant Technology<br/><br/>Glossary<br/><br/>2.29.1. Introduction<br/><br/>2.29.2. Mammalian Expression Vectors<br/><br/>2.29.3. Nonviral Gene Delivery<br/><br/>2.29.4. Cells<br/><br/>2.29.5. Host Cell Engineering<br/><br/>2.29.6. Generation of Recombinant Cell Lines<br/><br/>2.29.7. Transient Gene Expression<br/><br/>2.29.8. Regulatory Issues<br/><br/>2.30. Metabolic Regulation Analysis and Metabolic Engineering<br/><br/>Glossary<br/><br/>2.30.1. Introduction<br/><br/>2.30.2. Metabolic Engineering Practice<br/><br/>2.30.3. The Effect of Single-Gene Knockouts on the Metabolism<br/><br/>2.30.4. Global Regulators in Relation to the Cultural Environment<br/><br/>2.30.5. The Systems Biology Approach<br/><br/>2.30.6. Conclusion<br/><br/>2.31. Proteomics, Protein Engineering<br/><br/>Glossary<br/><br/>2.31.1. Introduction<br/><br/>2.31.2. Mass Spectrometry-Based Proteome Profiling Techniques<br/><br/>2.31.3. Current Advances in Protein Identification: Online and Microfluidic Proteomic Systems<br/><br/>2.31.4. Current Challenges in Proteomics<br/><br/>2.32. Heterologous Protein Expression<br/><br/>Glossary<br/><br/>2.32.1. Introduction<br/><br/>2.32.2. Heterologous Protein Expression in Bacterial Cultures<br/><br/>2.32.3. Heterologous Protein Expression in Yeast Culture<br/><br/>2.32.4. Heterologous Protein Expression in Insect Cell Culture<br/><br/>2.32.5. Heterologous Protein Expression in Mammalian Cell culture<br/><br/>2.32.6. Heterologous Protein Expression in Plant Cell Culture<br/><br/>2.32.7. Heterologous Protein Expression in Algal Cell Culture<br/><br/>2.32.8. Heterologous Protein Expression in Moss Culture<br/><br/>2.32.9. Heterologous Protein Expression in Cell-Free Systems<br/><br/>2.32.10. Summary and Future Directions<br/><br/>2.33. Biotransformations<br/><br/>Glossary<br/><br/>2.33.1. Introduction<br/><br/>2.33.2. Enzymes versus Whole Cells<br/><br/>2.33.3. Extremophiles as a Source of New Enzymes<br/><br/>2.33.4. Biotransformations as a Source of Chiral Compounds<br/><br/>2.33.5. Types of Reaction Systems<br/><br/>2.33.6. Industrial Processes – Overview on Present and Prospective Trends<br/><br/>2.34. Immobilized Enzymes<br/><br/>Glossary<br/><br/>2.34.1. Introduction<br/><br/>2.34.2. What Are Immobilized Enzymes?<br/><br/>2.34.3. Classification of Immobilized Enzymes<br/><br/>2.34.4. Approaches toward Robust Immobilized Enzymes<br/><br/>2.34.5. Engineering the Immobilized Enzymes<br/><br/>2.34.6. Prospectives and Future Developments<br/><br/>2.35. Immobilization Technology<br/><br/>Glossary<br/><br/>2.35.1. Introduction<br/><br/>2.35.2. Strategies for Cell Immobilization<br/><br/>2.35.3. Products Suitable for Immobilized Cells<br/><br/>2.35.4. Immobilized-Cell Bioreactors<br/><br/>2.35.5. Conclusions<br/><br/>2.36. Immobilized Viable Cell Biocatalysts<br/><br/>Glossary<br/><br/>2.36.1. Introduction: Development and Main Application Fields of Immobilized Cell Cultures<br/><br/>2.36.2. Original Motivation of Viable IC Technology<br/><br/>2.36.3. Current Data on IC Physiology<br/><br/>2.36.4. Proteomic Approach and Biofilm Phenotype<br/><br/>2.36.5. Conclusion<br/><br/>2.37. Fermentation Processes<br/><br/>Glossary<br/><br/>2.37.1. Introduction<br/><br/>2.37.2. Microbial Growth and Stoichiometry<br/><br/>2.37.3. Autocatalytic Nature of Microbial Growth<br/><br/>2.37.4. Cell Yields<br/><br/>2.37.5. Product Yields<br/><br/>2.38. Fed-Batch Fermentation – Design Strategies<br/><br/>Glossary<br/><br/>2.38.1. Introduction<br/><br/>2.38.2. Different Types of Fed-Batch Cultivations<br/><br/>2.38.3. Applications of Fed-Batch Cultivation<br/><br/>2.38.4. Control Techniques for Fed-Batch Fermentation<br/><br/>2.38.5. Design of Specific Fed-Batch Cultivation Strategies Using the Mathematical Model of the System<br/><br/>2.38.6. Model-Based Fed-Batch Cultivation Strategies<br/><br/>2.38.7. Parameters Used to Control the Fed-Batch Fermentations<br/><br/>2.38.8. Conclusion<br/><br/>2.39. Continuous Operation<br/><br/>Glossary<br/><br/>2.39.1. Introduction<br/><br/>2.39.2. Homogeneous System<br/><br/>2.39.3. Heterogeneous Systems<br/><br/>2.40. Multistage Continuous High Cell Density Culture<br/><br/>Glossary<br/><br/>2.40.1. Introduction<br/><br/>2.40.2. Historical Background<br/><br/>2.40.3. High Cell Density Culture<br/><br/>2.40.4. Multistage Continuous HCDC<br/><br/>2.40.5. Summary<br/><br/>2.41. Integrated Production and Separation<br/><br/>Glossary<br/><br/>2.41.1. Introduction<br/><br/>2.41.2. Integration Methodology for Reducing Process Step<br/><br/>2.41.3. Cross-Sectional Technologies through Integration Methodology<br/><br/>2.41.4. Separation Techniques for the Integration in Terms of Product Characteristics<br/><br/>2.41.5. Bioreactor Configuration for the Integration of Production and Separation<br/><br/>2.41.6. Techniques for ISPR<br/><br/>2.41.7. Process Integration by Biotechnology<br/><br/>2.41.8. Perspective for the Process Integration<br/><br/>2.42. Product Recovery<br/><br/>Glossary<br/><br/>2.42.1. Introduction<br/><br/>2.42.2. Historical Background<br/><br/>2.42.3. Modular Unit Operations in Downstream Processing<br/><br/>2.42.4. Integrated Unit Operations in Downstream Processing<br/><br/>2.42.5. Product Purification<br/><br/>2.42.6. Product Formulation and Stabilization<br/><br/>2.42.7. Conclusion<br/><br/>2.43. Membrane Systems and Technology<br/><br/>Glossary<br/><br/>2.43.1. Introduction<br/><br/>2.43.2. Membrane Materials<br/><br/>2.43.3. Membrane Configurations<br/><br/>2.43.4. Characterization of Membranes<br/><br/>2.43.5. Solute and Particle Deposition<br/><br/>2.43.6. Membrane Cleaning<br/><br/>2.43.7. Ultrafiltration and Microfiltration<br/><br/>2.43.8. Membrane Bioreactors<br/><br/>2.43.9. Membrane Chromatography<br/><br/>2.43.10. Membrane Contactors<br/><br/>2.43.11. Conclusion<br/><br/>2.44. Cell Disruption<br/><br/>Glossary<br/><br/>2.44.1. Introduction<br/><br/>2.44.2. Characteristics of the Microbial Cell Influencing Resistance to Disruption<br/><br/>2.44.3. Approaches to Microbial Cell Disruption<br/><br/>2.44.4. Large-Scale Cell Disruption Technologies<br/><br/>2.44.5. Laboratory-Scale, and Developing, Cell Disruption Technologies<br/><br/>2.44.6. Selective Product Release<br/><br/>2.44.7. Pretreatment to Augment Product Release<br/><br/>2.44.8. Integration of Biomass Formation and Product Release<br/><br/>2.44.9. Integration of Product Release and Product Recovery and Purification<br/><br/>2.44.10. Closing Remarks<br/><br/>2.45. Autolysis of Yeasts<br/><br/>Glossary<br/><br/>2.45.1. Introduction<br/><br/>2.45.2. Yeast Autolysis Mechanism<br/><br/>2.45.3. Yeast Autolysis Compounds<br/><br/>2.45.4. Conclusion<br/><br/>2.46. Precipitation and Crystallization<br/><br/>Glossary<br/><br/>Acknowledgments<br/><br/>2.46.1. Introduction<br/><br/>2.46.2. Solid–Liquid Equilibrium: Phase Diagrams<br/><br/>2.46.3. Modeling of Solid–Liquid Equilibrium<br/><br/>2.46.4. Crystallization of Proteins<br/><br/>2.46.5. Developing a Protein Crystallization Process<br/><br/>2.47. Adsorption and Chromatography<br/><br/>Glossary<br/><br/>2.47.1. Introduction<br/><br/>2.47.2. Molecular Interactions in Adsorption<br/><br/>2.47.3. Chromatographic Methods<br/><br/>2.47.4. Theoretical Aspects of Adsorption and Chromatography<br/><br/>2.47.5. Development of Adsorption and Chromatography<br/><br/>2.47.6. Conclusions<br/><br/>2.48. Modeling Chromatographic Separation<br/><br/>Glossary<br/><br/>2.48.1. Introduction<br/><br/>2.48.2. Theoretical Background<br/><br/>2.48.3. Models for Chromatography<br/><br/>2.48.4. Case Studies<br/><br/>2.48.5. Summary<br/><br/>2.49. Aqueous Two-Phase Systems<br/><br/>Glossary<br/><br/>2.49.1. Introduction<br/><br/>2.49.2. Theoretical Background<br/><br/>2.49.3. Application of ATPSs for the Recovery of Biological Products<br/><br/>2.49.4. Conclusions<br/><br/>2.50. Foam Separations<br/><br/>Glossary<br/><br/>2.50.1. Introduction<br/><br/>2.50.2. Applications of Foam Fractionation<br/><br/>2.50.3. Mechanism of Foam Fractionation<br/><br/>2.50.4. Design<br/><br/>2.50.5. Process Intensification<br/><br/>2.51. Drying<br/><br/>Glossary<br/><br/>2.51.1. Introduction<br/><br/>2.51.2. Applications<br/><br/>2.51.3. Traditional Drying Processes<br/><br/>2.51.4. Other Drying Technologies<br/><br/>2.51.5. Summary<br/><br/>2.52. Chiral Separations<br/><br/>Glossary<br/><br/>2.52.1. General Introduction<br/><br/>2.52.2. Crystallization<br/><br/>2.52.3. Chromatography<br/><br/>2.52.4. Capillary Electrophoresis<br/><br/>2.52.5. Liquid–Liquid Extraction<br/><br/>2.52.6. Membrane-Assisted Separations<br/><br/>2.52.7. Inclusion Distillation and Precipitation<br/><br/>2.53. Lab on a Chip – Future Technology for Characterizing Biotechnology Products<br/><br/>Glossary<br/><br/>Acknowledgments<br/><br/>2.53.1. Introduction<br/><br/>2.53.2. Technology<br/><br/>2.53.3. Components<br/><br/>2.53.4. Applications<br/><br/>2.53.5. Concluding Remarks<br/><br/>2.54. Protein Refolding/Renaturation<br/><br/>Glossary<br/><br/>2.54.1. Introduction<br/><br/>2.54.2. Inclusion Bodies<br/><br/>2.54.3. Isolation and Purification of Inclusion Bodies<br/><br/>2.54.4. Solubilization of Inclusion Bodies<br/><br/>2.54.5. Mechanism of Protein Aggregation<br/><br/>2.54.6. Renaturation of Denatured Protein<br/><br/>2.54.7. Concluding Remarks<br/><br/>2.55. Biogas Production<br/><br/>Glossary<br/><br/>2.55.1. Introduction<br/><br/>2.55.2. Advantages of the AD Processes<br/><br/>2.55.3. Microbiology of AD<br/><br/>2.55.4. Factors Affecting the AD Process<br/><br/>2.55.5. Types of Anaerobic Reactors<br/><br/>2.55.6. Effect of Operational and Environmental Variations on AD<br/><br/>2.55.7. Biogas Utilization<br/><br/>2.55.8. Biogas Upgrading Methods<br/><br/>2.55.9. Applications of AD Technology<br/><br/>2.56. Purification Process Design and the Influence of Product and Technology Platforms<br/><br/>Glossary<br/><br/>2.56.1. Introduction<br/><br/>2.56.2. Impurities<br/><br/>2.56.3. Purification Unit Operations<br/><br/>2.56.4. Purification Process Flow-Sheet Organization and Design<br/><br/>2.56.5. Processing Platforms – Examples and Characteristics<br/><br/>2.56.6. Conclusions<br/><br/>2.57. The Proportion of Downstream Costs in Fermentative Production Processes<br/><br/>Glossary<br/><br/>2.57.1. Introduction<br/><br/>2.57.2. Overview of literature data<br/><br/>2.57.3. Conclusions<br/><br/>2.58. Biorefinery Engineering<br/><br/>Glossary<br/><br/>Acknowledgments<br/><br/>2.58.1. Introduction<br/><br/>2.58.2. Feedstock Availability<br/><br/>2.58.3. Platform of Bioprocess Technologies<br/><br/>2.58.4. Examples of Current Improvements of Key Biorefinery Processes<br/><br/>2.58.5. Prospect<br/><br/>2.59. Instrumentation and Analytical Methods<br/><br/>2.59.1. Introduction<br/><br/>2.59.2. Physical Process Parameters<br/><br/>2.59.3. Cell Mass Measurements<br/><br/>2.59.4. Analysis of Substrates and Products<br/><br/>2.59.5. Miscellaneous Techniques<br/><br/>2.59.6. Conclusions and Remarks<br/><br/>2.60. Life Cycle Assessment in Biotechnology<br/><br/>Glossary<br/><br/>2.60.1. Introduction<br/><br/>2.60.2. The Methodology of LCA<br/><br/>2.60.3. LCA: Utility and Limitations<br/><br/>2.60.4. Application of LCA in Food Biotechnology<br/><br/>2.60.5. Application of LCA in Pharmaceutical Biotechnology<br/><br/>2.60.6. Application of LCA in Biopolymers<br/><br/>2.60.7. Application of LCA in Biofuels<br/><br/>2.60.8. Application of LCA in Biodegradable Waste Management<br/><br/>2.60.9. Some New Tendencies<br/><br/>2.61. Metabolic Control<br/><br/>Glossary<br/><br/>Acknowledgments<br/><br/>2.61.1. Introduction<br/><br/>2.61.2. Regulation of Biological Systems<br/><br/>2.61.3. Control of Biological Systems<br/><br/>2.61.4. Network Rigidity<br/><br/>2.61.5. Biochemical Systems Theory<br/><br/>2.61.6. Metabolic Control Analysis<br/><br/>2.61.7. Determination of the Flux Control Coefficients<br/><br/>2.61.8. In Vivo Applications<br/><br/>2.61.9. Conclusion<br/><br/>2.62. Fuzzy Control of Bioprocess<br/><br/>Glossary<br/><br/>2.62.1. Direct Inference of Process Variables<br/><br/>2.62.2. Determination of Process Variables Based on Identification of Culture Phase<br/><br/>2.62.3. Combination of Fuzzy Inference with Other Methods<br/><br/>2.62.4. Conclusion<br/><br/>2.63. Online Control Strategies<br/><br/>Glossary<br/><br/>Acknowledgment<br/><br/>2.63.1. Introduction<br/><br/>2.63.2. Current Practice of Bioprocess Control<br/><br/>2.63.3. Advanced Process Control Strategies<br/><br/>2.63.4. Concluding Remarks<br/><br/>2.64. Process Optimization<br/><br/>Glossary<br/><br/>2.64.1. Introduction<br/><br/>2.64.2. Review of the Most Relevant Optimization Techniques<br/><br/>2.64.3. Case Studies<br/><br/>2.64.4. Conclusions<br/><br/>2.65. Micro-Biochemical Engineering<br/><br/>Glossary<br/><br/>Acknowledgments<br/><br/>2.65.1. Introduction<br/><br/>2.65.2. Overview of Micro-Biochemical Engineering<br/><br/>2.65.3. Examples of Micro-Biochemical Engineering<br/><br/>2.65.4. Future Challenges in Applying Micro-Biochemical Engineering<br/><br/>2.65.5. Conclusions<br/><br/>2.66. Sustainability<br/><br/>Glossary<br/><br/>2.66.1. Introduction<br/><br/>2.66.2. About Sustainability<br/><br/>2.66.3. Spatial and Temporal Dimensions of Sustainability<br/><br/>2.66.4. Challenges of Sustainability<br/><br/>2.66.5. Indicators of Sustainability<br/><br/>2.66.6. Keys to Sustainable Development in Practice<br/><br/>2.66.7. Biotechnology and Sustainability<br/><br/>2.66.8. Renewable Resources and Energy<br/><br/>2.66.9. Concluding Remarks<br/><br/>2.67. Nanostructured Biocatalysts<br/><br/>Glossary<br/><br/>2.67.1. Introduction<br/><br/>2.67.2. Nonaqueous Enzymatic Catalysis<br/><br/>2.67.3. Enzymes in Nanostructures<br/><br/>2.67.4. Preparation of Enzyme Nanogels<br/><br/>2.67.5. Molecular Fundamentals of Enzyme Nanogels<br/><br/>2.67.6. Potential Applications of Enzyme Nanogels as Biocatalysts<br/><br/>2.67.7. Summary<br/><br/>2.68. Aseptic Operations<br/><br/>Glossary<br/><br/>2.68.1. Introduction<br/><br/>2.68.2. Design and Procedural Approaches to Minimizing Contamination<br/><br/>2.68.3. Fermentation/Cell Culture Considerations<br/><br/>2.68.4. Considerations for Purification and Formulation/Fill<br/><br/>2.68.5. Validation and Verification<br/><br/>2.68.6. Sterility Analysis and Culture Purity<br/><br/>2.68.7. Summary<br/><br/>2.69. Oxygen Mass Transfer in Bioreactors<br/><br/>Glossary<br/><br/>2.69.1. Introduction<br/><br/>2.69.2. Effect of Various Parameters on Oxygen Mass Transfer<br/><br/>2.69.3. Conclusions<br/><br/>2.70. Cavitation in Biotechnology<br/><br/>Glossary<br/><br/>2.70.1. Introduction<br/><br/>2.70.2. Reactor Designs<br/><br/>2.70.3. Different Applications of Cavitation<br/><br/>2.70.3.7. Concluding Remarks<br/><br/>2.71. Flow Cytometry<br/><br/>Glossary<br/><br/>2.71.1. Introduction<br/><br/>2.71.2. Description of the FC Technique<br/><br/>2.71.3. Cell Viability and Functionality<br/><br/>2.71.4. Applications to Industrial Bioprocesses<br/><br/>2.71.5. Monitoring and Control of Biotransformations<br/><br/>2.71.6. Theoretical Applications: Kinetic Modeling<br/><br/>2.71.7. Devices of Practical Use and Automation of FC Equipments<br/><br/>2.71.8. Conclusions<br/><br/>2.72. Cleaning in Place<br/><br/>Glossary<br/><br/>2.72.1. Introduction<br/><br/>2.72.2. Hygiene Agents<br/><br/>2.72.3. Overview of CIP Systems<br/><br/>2.72.4. Cleaning Principles<br/><br/>2.72.5. Other Technological Aspects<br/><br/>2.73. Ionic Liquids<br/><br/>Glossary<br/><br/>2.73.1. Introduction<br/><br/>2.73.2. Applications of Enzymes in Ionic Liquids<br/><br/>2.73.3. Environmental Impact of Ionic Liquids<br/><br/>2.73.4. Conclusions<br/><br/>2.74. Supercritical Fluids<br/><br/>Glossary<br/><br/>2.74.1. Introduction<br/><br/>2.74.2. Pure Substances as Supercritical Fluids<br/><br/>2.74.3. Properties of Supercritical Fluids<br/><br/>2.74.4. Modifiers<br/><br/>2.74.5. Solubility in a Supercritical Fluid<br/><br/>2.74.6. Calculations to Predict Whether a Modifier Is Required<br/><br/>2.74.7. Supercritical Fluid Extraction<br/><br/>2.74.8. Supercritical Fluid Chromatography<br/><br/>2.74.9. Supercritical Fluid Particle Engineering<br/><br/>2.74.10. Supercritical Fluid Tissue Engineering and Regenerative Medicine<br/><br/>2.74.11. Supercritical Fluids as Alternative Enzymatic Reaction Solvents<br/><br/>2.74.12. Sterilization Using SF-CO2<br/><br/>2.74.13. Critical Point Drying of Biological Samples<br/><br/>2.74.14. Summary<br/><br/>2.75. Computational Fluid Dynamics<br/><br/>Glossary<br/><br/>Acknowledgment<br/><br/>2.75.1. Introduction<br/><br/>2.75.2. Fundamentals<br/><br/>2.75.3. Single-Phase Flow Simulations<br/><br/>2.75.4. Multiphase Flow Simulations<br/><br/>2.75.5. CFD in Biochemical Engineering<br/><br/>2.75.6. Conclusions and Future Perspectives |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | AC Sinha Collection |
| Withdrawn status | Lost status | Damaged status | Not for loan | Collection Type | Home library | Current library | Shelving location | Date acquired | Full call number | Accession number | Date last seen | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Not For Loan | Reference Collection | Central Library, Sikkim University | Central Library, Sikkim University | Reference | 29/08/2016 | 660.6 MOO/C | P35150 | 23/09/2022 | Reference Books |