000 03594cam a2200493 i 4500
001 on1019950992
003 OCoLC
005 20250612155453.0
006 m o d
007 cr |n|||||||||
008 180120s2018 enk ob 001 0 eng d
010 _a 2017959512
040 _aYDX
_beng
_erda
_epn
_cYDX
_dN$T
_dEBLCP
_dN$T
_dOCLCO
_dUIU
_dOPELS
_dOCLCF
_dSNM
_dTXM
_dD6H
_dSNK
_dIAY
_dCASUM
_dOCLCO
_dUAB
_dOCLCO
_dINT
_dOCLCQ
_dOCLCO
_dU3W
_dOCLCO
_dYDX
_dIAD
_dOCLCO
_dLVT
_dOCLCA
_dOCLCQ
_dS2H
_dOCLCO
_dOCLCQ
_dVT2
_dOCLCO
_dAAA
_dOCLCO
_dOCLCQ
_dOCLCA
_dBRX
_dOCL
_dOCLCA
_dOCLCO
_dOCLCL
_dUKKRT
_dOCLCQ
_dOCLCO
016 7 _a101725976
_2DNLM
019 _a1019708709
_a1020062536
_a1031884941
_a1046105591
_a1108311854
_a1229808501
_a1235826863
020 _a9780128143940
_q(electronic bk.)
020 _a0128143940
_q(electronic bk.)
020 _z0128143932
020 _z9780128143933
035 _a(OCoLC)1019950992
_z(OCoLC)1019708709
_z(OCoLC)1020062536
_z(OCoLC)1031884941
_z(OCoLC)1046105591
_z(OCoLC)1108311854
_z(OCoLC)1229808501
_z(OCoLC)1235826863
050 4 _aRM301.3.G45
_bB47 2018eb
060 4 _a2018 D-100
060 4 _aWB 102
072 7 _aMED
_x071000
_2bisacsh
082 0 4 _a615.8/95
_223
100 1 _aBerman, Jules J.,
_eauthor.
_1https://id.oclc.org/worldcat/entity/E39PCjB7VXkQdjtq3Bj3CMWQRq
_934069
245 1 0 _aPrecision medicine and the reinvention of human disease /
_cJules J. Berman.
264 1 _aLondon, UK :
_bAcademic Press, an imprint of Elsevier,
_c[2018]
300 _a1 online resource
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
504 _aIncludes bibliographical references and index.
505 0 _aIntroduction: seriously, what is precision medicine? -- Redefining disease causality -- Genetics: clues, not answers to the mysteries of precision medicine -- Disease convergence -- The precision of the rare diseases -- Precision organisms -- Reinventing diagnosis -- Precision data -- The alternate futures of precision medicine.
520 _aDespite what you may have read in the popular press and in social media, Precision Medicine is not devoted to finding unique treatments for individuals, based on analyzing their DNA. To the contrary, the goal of Precision Medicine is to find general treatments that are highly effective for large numbers of individuals who fall into precisely diagnosed groups. We now know that every disease develops over time, through a sequence of defined biological steps, and that these steps may differ among individuals, based on genetic and environmental conditions. We are currently developing rational therapies and preventive measures, based on our precise understanding of the steps leading to the clinical expression of diseases. Precision Medicine and the Reinvention of Human Disease explains the scientific breakthroughs that have changed the way that we understand diseases, and reveals how medical scientists are using this new knowledge to launch a medical revolution.
650 0 _aGenomics.
650 0 _aPrecision medicine.
_934070
650 0 _aPharmacogenetics.
_917494
650 0 _aHuman chromosome abnormalities
_xDiagnosis.
_934071
650 0 _aHuman beings.
758 _ihas work:
_aPrecision medicine and the reinvention of human disease (Text)
_1https://id.oclc.org/worldcat/entity/E39PCFwdhTmhJHyfD8yDTFVdw3
_4https://id.oclc.org/worldcat/ontology/hasWork
776 0 8 _iPrint version:
_z0128143932
_z9780128143933
_w(OCoLC)1010621928
856 4 0 _3ScienceDirect
_uhttps://www.sciencedirect.com/science/book/9780128143933
999 _c216436
_d216436