000 | 01485aam a22003374a 4500 | ||
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999 |
_c195395 _d195395 |
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020 | _a052180177X | ||
040 | _cCUS | ||
082 | 0 | 4 |
_a572.80285 _bDWY/G |
100 | 1 | _aDwyer, Rex A. | |
245 | 1 | 0 |
_aGenomic perl: from bioinformatics basics to working code / _cRex A. Dwyer |
260 |
_aCambridge, UK ; _aNew York : _bCambridge University Press, _c2003. |
||
300 | _axvii, 334 p. | ||
505 | _aThe Central Dogma -- DNA and RNA -- Chromosomes -- Proteins -- The Central Dogma -- Transcription and Translation in Perl -- RNA Secondary Structure -- Messenger and Catalytic RNA -- Levels of RNA Structure -- Constraints on Secondary Structure -- RNA Secondary Structures in Perl -- Counting Hydrogen Bonds -- Folding RNA -- Comparing DNA Sequences -- DNA Sequencing and Sequence Assembly -- Alignments and Similarity -- Alignment and Similarity in Perl -- Predicting Species: Statistical Models -- Perl Subroutine Libraries -- Species Prediction in Perl -- Substitution Matrices for Amino Acids -- More on Homology -- Deriving Substitution Matrices from Alignments -- Substitution Matrices in Perl -- The PAM Matrices -- PAM Matrices in Perl -- Sequence Databases -- FASTA Format -- GenBank Format -- GenBank's Feature Locations -- Reading Sequence Files in Perl -- Object-Oriented Programming in Perl -- The SimpleReader Class -- Hiding File Formats with Method Inheritance -- Local Alignment and the BLAST Heuristic -- The Smith-Waterman Algorithm -- The BLAST Heuristic -- Preprocessing the Query String -- Scanning the Target String -- Implementing BLAST in Perl -- Statistics of BLAST Database Searches -- BLAST Scores for Random DNA -- BLAST Scores for Random Residues -- BLAST Statistics in Perl -- Interpreting BLAST Output -- Multiple Sequence Alignment I -- Extending the Needleman-Wunsch Algorithm -- NP-Completeness -- Alignment Merging: A Building Block for Heuristics -- Merging Alignments in Perl -- Finding a Good Merge Order. | ||
650 | 0 | _aPerl (Computer program language) | |
650 | 0 |
_aMolecular biology _xData processing. |
|
650 | 0 | _aBioinformatics. | |
942 | _cWB16 |