000 01417nam a2200169Ia 4500
999 _c186444
_d186444
020 _a1555818935
040 _cCUS
082 _a615.329
_bCHR/A
100 _aWalsh, Christopher.
_9782
245 0 _aAntibiotics: aqctions, origins, resistance/
_cChristopher Walsh
260 _aWashington:
_bASM Press,
_c2003.
300 _ax, 335 p. :
_bill. ;
_c26 cm.
505 _a1 Antibiotics : initial concepts 2 Introduction to major antibiotic classes and modes of action 3 Antibiotics that act on cell wall biosynthesis 4 Antibiotics that block bacterial protein biosynthesis 5 Antibiotics that block DNA replication and repair : the Quinolones 6 Other targets of antibacterial drugs 7 Natural and producer immunity versus acquired resistance 8 Enzymatic destruction or modification of the antibiotic by resistant bacteria 9 Antibiotic resistance by efflux pumps 10 Antibiotic resistance by replacement or modification of the antibiotic target 11 Regulation of antibiotic biosynthesis in producer organisms 12 Polyketide antibiotic biosynthesis : assembly line enzymology 13 Enzymatic assembly lines for nonribosomal peptide antibiotics 14 Biosynthesis of other classes of antibiotics 15 New looks at targets 16 New molecules 17 Contexts and challenges for the use of new antibiotics.
650 _aAntibiotics
_9783
650 _aDrug resistance in microorganisms
_9784
942 _cWB16
_05