000 | 02283cam a22002414a 4500 | ||
---|---|---|---|
999 |
_c167787 _d167787 |
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020 | _a9780470741856 (hardcover) | ||
020 | _a9780470741849 (softcover) | ||
040 | _cCUS | ||
082 |
_a572.8 _bDAL/M |
||
100 | 1 |
_aDale, Jeremy _919764 |
|
245 | 1 | 0 |
_aMolecular genetics of bacteria/ _cJeremy W. Dale and Simon Park. |
250 | _a5th ed. | ||
260 |
_aChichester, West Sussex, England ; _bWiley-Blackwell, _c2010. |
||
300 |
_axiii, 388 p. : _bill. ; _c25 cm. |
||
504 | _aIncludes bibliographical references (p. [333]-335) and index. | ||
505 | _aNucleic Acid Structure and Function -- Structure of nucleic acids -- DNA -- RNA -- Hydrophobic interactions -- Different forms of the double helix -- Supercoiling -- Denaturation and hybridization -- Orientation of nucleic acid strands -- Replication of DNA -- Unwinding and rewinding -- Fidelity of replication: proof-reading -- Chromosome replication and cell division -- DNA repair -- Mismatch repair -- Excision repair -- Recombination (post-replication) repair -- SOS repair -- Gene expression -- Transcription -- Translation -- Post-translational events -- Gene organization -- Mutation and Variation -- Variation and evolution -- Fluctuation test -- Directed mutation in bacteria? -- Types of mutations -- Point mutations -- Conditional mutants -- Variation due to larger scale DNA alterations -- Extrachromosomal agents and horizontal gene transfer -- Phenotypes -- Restoration of phenotype -- Reversion and suppression -- Complementation -- Recombination -- Mechanisms of mutation -- Spontaneous mutation -- Chemical mutagens -- Ultraviolet irradiation -- Isolation and identification of mutants -- Mutation and selection -- Replica plating -- Penicillin enrichment -- Isolation of other mutants -- Molecular methods -- Regulation of Gene Expression -- Gene copy number -- Transcriptional control -- Promoters -- Terminators, attenuators and anti-terminators -- Induction and repression: regulatory proteins -- Attenuation: trp operon -- Two-component regulatory systems -- Global regulatory systems. | ||
650 | 0 |
_aBacterial genetics. _919765 |
|
650 | 0 |
_aMicrobial genetics. _99514 |
|
650 | 0 |
_aMolecular genetics. _95129 |
|
650 | 0 | _aGenetic engineering. | |
700 | 1 |
_aPark, Simon _919766 |
|
942 |
_cWB16 _01 |