000 00355nam a2200133Ia 4500
999 _c152679
_d152679
020 _a9780470712368
040 _cCUS
082 _a547.2
_bWAR/O
100 _aWarren, Stuart
245 0 _aOrganic synthesis the disconnection approach/
_cStuart Warren and Paul Wyatt
250 _a2nd ed.
260 _aLondon:
_bJohn Wiley & Sons,
_c2008.
300 _aviii, 329 p. :
_bill. ;
_c25 cm.
505 _aThe disconnection approach -- Basic principles : synthons and reagents synthesis of aromatic compounds -- Strategy I : the order of events -- One-group C-X disconnections -- Strategy II : chemoselectivity -- Two-group C-X disconnections -- Strategy III : reversal of polarity, cyclisations, summary of strategy -- Amine synthesis -- Strategy IV : protecting groups -- One group C-C disconnections I : alcohols -- General strategy A : choosing a disconnection -- Strategy V : stereoselectivity A -- One group C-C disconnections II : carbonyl compounds -- Strategy VI : regioselectivity -- Alkene synthesis -- Strategy VII : use of acetylenes (alkynes) -- Two-group C-C disconnections I : Diels-Alder reactions -- Strategy VIII : introduction to carbonyl condensations -- Two-group C-C disconnections II : 1,3-difunctionalised compounds -- Strategy IX : control in carbonyl condensations -- Two-group C-C disconnections : 1,5-difunctionalised compounds conjugate (Michael) addition and Robinson annelation -- Strategy X : aliphatic nitro compounds in synthesis -- Two-group disconnections IV : 1,2-difunctionalised compounds -- Strategy XI : radical reactions in synthesis -- Two-group disconnections V : 1,4-difunctionalised compounds -- Strategy XII : reconnection -- Two-group C-C disconnections VI : 1,6-diCarbonyl compounds -- General strategy B : strategy of carbonyl disconnections -- Strategy XIII : introduction to ring synthesis : saturated heterocycles -- Three-membered rings -- Strategy XIV : rearrangements in synthesis -- Four-membered rings : photochemistry in synthesis -- Strategy XV : the use of ketenes in synthesis -- Five-membered rings -- Strategy XVI : pericyclic reactions in synthesis : special methods for five-membered rings -- Six-membered rings -- General strategy C : strategy of ring synthesis -- Strategy XVII : stereoselectivity B -- Aromatic heterocycles -- General strategy D : advanced strategy.
650 _aOrganic compounds--Synthesis
700 _aWyatt, Paul
942 _cSC79