000			02168nam a2200253Ia 4500
003			OSt
005			20220427161724.0
008			220427b |||||||| |||| 00| 0 eng d
020			_a9781405135443
040			_cCUS
082			_a660.65 _bPRI/P
100			_aPrimrose, S.B. _97493
245		0	_aPrinciples of Gene Manipulation and Genomics
250			_a7th ed.
260			_aUSA: _bBlackwell Publishing, _c2006.
300			_axxii, 644p. : _bill. ; _c28 cm.
505			_a1 Gene manipulation in the post-genomics era Part I Fundamental Techniques of Gene Manipulation 2 Basic techniques 3 Cutting and joining DNA molecules, cutting DNA molecules 4 Basic biology of plasmid and phage vectors, plasmid biology and simple plasmid vectors 5 Cosmids, phasmids, and other advanced vectors, vectors for cloning large fragments of DNA 6 Gene-cloning strategies 7 Sequencing genes and short stretches of DNA 8 Changing genes: site-directed mutagenesis and protein engineering 9 Bioinformatics Part II Manipulating DNA in microbes, plants, and animals 10 Cloning in bacteria other than escherichia coli 11 Cloning in saccharomyces cerevisiae and other fungi 12 Gene transfer to animal cells 13 Genetic manipulation of animals 14 Gene transfer to plants 15 Advanced transgenic technology Part III Genome analysis, genomics, and beyond 16 The organization and structure of genomes 17 Mapping and sequencing genomes 18 Comparative genomics 19 Large-scale mutagenesis and interference 20 Analysis of the transcriptome 21 Proteomics I-expression analysis and characterization of proteins 22 Proteomics II-analysis of protein structures 23 Proteomics III-protein interactions 24 Metabolomics and global biochemical networks Part IV Applications of gene manipulation and genomics 25 Applications of genomics: understanding the basis of polygenic disorders and identifying quantitative trait loci 26 Applications of recombinant DNA technology
650			_aGenetic Engineering
650			_aGenomics _97495
650			_aGene Mapping _97496
650			_aNucleotide Sequence _97497
700			_aTwyman, R.M. _97494
942			_cSC79 _2ddc
999			_c147404 _d147404