000			00383nam a2200145Ia 4500
999			_c146535 _d146535
020			_a9780824706074
040			_cCUS
082			_a543.0873 _bROS/M
245		0	_aMass spectrometry in drug discovery/ _cRossi, David T.
250			_a1st ed.
260			_aNew York: _bMarcel and Dekker, _c2002.
300			_a420 p.
505			_aI Introduction 1 Demand for drug discovery today 2 The impact of atmospheric pressure ionization II Instrumentation 3 A mass spectrometry primer III Experimental strategies 4 Ion chemistry and fragmentation 5 The LC/MS experiment 6 Sample preparation and handling for LC/MS in drug discovery IV Applications 7 Mass spectrometry in combinatorial chemistry 8 Drug hydrophobicity and transport 9 The mass spectrometer in drug metabolism 10 Mass spectrometry-assisted applications of stable-labeled compounds in pharmacokinetic and drug metabolism studies 11 Cassette dosing in drug discovery 12 Applications of microdialysis/mass spectrometry to drug discovery 13 Future directions for mass spectrometry in drug discovery
942			_cAC8