000 00326nam a2200121Ia 4500
999 _c145413
_d145413
020 _a9780121995041
040 _cCUS
082 _a581.15
_bCUR/A
245 0 _aAdenoviral vectors for gene therapy/
_cedited by David T. Curiel, Joanne T. Douglas.
250 _a1st ed.
260 _aAmsterdam:
_bAcademic Press,
_c2002.
300 _axxviii, 677 p. :
_bill. ;
_c24 cm.
505 _a1 Adenovirus Structure 2 Biology of Adenovirus Cell Entry 3 Adenovirus Replication 4 Adenoviral Vector Construction I: Mammalian Systems 5 Adenoviral Vector Construction II: Bacterial Systems 6 Propagation of Adenoviral Vectors: Use of PER.C6 Cells 7 Purification of Adenovirus 8 Targeted Adenoviral Vectors I: Transductional Targeting 9 Targeted Adenoviral Vectors II: Transcriptional Targeting 10 Development of Attenuated Replication Competent Adenoviruses (ARCAs) for the treatment of Prostate Cancer 11 Replication-Selective Oncolytic Adenovirus EI-Region Mutants: Virotherapy for Cancer 12 Innate Immune Responses to in Vivo Adenovirus Infection 13 Humoral Immune Response 14 Novel Methods to Eliminate the Immune Response to Adenovirus Gene Therapy 15 High-Capacity "Gutless" Adenoviral Vectors: Technical Aspects and Applications 16 Xenogenic Adenoviral Vectors 17 Hybrid Adenoviral Vectors 18 Utiliity of Adenoviral Vectors in Animal Models of Human Disease I: Cancer 19 Utiltity of Adenoviral Vectors in Animal Models of Human Disease II: Genetic Disease 20 Utility of Adenoviral Vectors in Animal Models of Human Disease III: Acquired Diseases 21 Testing of Adenoviral Vector Gene Transfer Products: FDA Expectations 22 Imaging Adenovirus-Medicated Gene Transfer
650 _aAndovirus
650 _aGene Therapy
700 _aedited by Curiel, David T.
700 _aDouglas, Joanne T.
942 _cSC79