TY  - BOOK
AU  - Berman,Jules J.
TI  - Precision medicine and the reinvention of human disease
SN  - 9780128143940
AV  - RM301.3.G45 B47 2018eb
U1  - 615.8/95 23
PY  - 2018///]
CY  - London, UK
PB  - Academic Press, an imprint of Elsevier
KW  - Genomics
KW  - Precision medicine
KW  - Pharmacogenetics
KW  - Human chromosome abnormalities
KW  - Diagnosis
KW  - Human beings
N1  - Includes bibliographical references and index; Introduction: seriously, what is precision medicine? -- Redefining disease causality -- Genetics: clues, not answers to the mysteries of precision medicine -- Disease convergence -- The precision of the rare diseases -- Precision organisms -- Reinventing diagnosis -- Precision data -- The alternate futures of precision medicine
N2  - Despite what you may have read in the popular press and in social media, Precision Medicine is not devoted to finding unique treatments for individuals, based on analyzing their DNA. To the contrary, the goal of Precision Medicine is to find general treatments that are highly effective for large numbers of individuals who fall into precisely diagnosed groups. We now know that every disease develops over time, through a sequence of defined biological steps, and that these steps may differ among individuals, based on genetic and environmental conditions. We are currently developing rational therapies and preventive measures, based on our precise understanding of the steps leading to the clinical expression of diseases. Precision Medicine and the Reinvention of Human Disease explains the scientific breakthroughs that have changed the way that we understand diseases, and reveals how medical scientists are using this new knowledge to launch a medical revolution
UR  - https://www.sciencedirect.com/science/book/9780128143933
ER  -