TY - BOOK AU - Witkowski, Jan A., ed. TI - The inside story: DNA to RNA to protein SN - 9780879697501 U1 - 572.809 PY - 2005/// CY - New York PB - Cold Spring Harbor Laboratory Press KW - Proteins--Synthesis KW - RNA KW - DNA KW - Biochemistry N1 - The general idea / Tim Hunt -- Albrecht Kossel / S. Rapoport -- Albrecht Kossel and the discovery of histones / Detlef Doenecke and Peter Karlson -- Early Nucleic acid chemistry / Fritz Schlenk -- P.A. Levene and 2-Deosy-D-ribose / Joseph S. Fruton -- Schrodinger's White is Life?: A 50-year reflection / G. Rickey Welch -- Schrodinger's What is Life?: Entropy, order and hereditary code-scripts / J.A. Witkowski -- Finally the beginnings of molecular biology / Seymour S. Cohen -- Biochemical origins of molecular biology: a discussion / Robert Olby -- The biological role of nucleic acids/ Peter Karlson -- Did a tragic accident delay the discovery of the double helical structure of DNA? / Keith L. Manchester -- Teh double helix and all that / H.R. Wilson -- Light on a dark lady / Anne Piper -- The DNA replication problem, 1953-1958 / Frederic L. HOlmes -- Tritium-labeled thymidine and early insights in DNA replication and chromosome structure / J. Herbert Taylor -- DNA replication: the 30th Anniversary of the bacterial model and the "Baby machine" / Stephen Cooper -- DNA strand separation, renaturation and hybridization / Julius Marmur -- Blotting at 25 / Ed M. Southern -- One chromosome: one DNA molecule / Bruno H. Zimm -- Through the looking glass: the discovery of supercoiled DNA / Jacob Lebowitz. Ernest F. Gale and proteni synthesis: the difficulties of analysing a complex system / Hans-Jorg Rheinberger -- Reminiscences about nucleic acid cytochemistry and biochemistry / Jean Brachet -- Jean Brachet's alternative scheme for protein synthesis / Denis Thieffry and Richard M. Burian -- Deciphering the genetic code- a personal account / Marshall Nirenberg -- The history of deciphering the genetic code: setting the record straight / Akira Kaji and Hideko Kaji -- Biocheistry or molecular biology? The discovery of "soluble RNA", / Mahlon Hoagland -- Back to Camelot: defining the specific role of tRNA in protein synthesis / Bernard Weisblum -- The crystallization and structural determination of tRNA / Brian F.C. Clark -- What was the message? / Elliot Volking -- An RNA heresy in the fifties / Henry Harris -- The discovery of "Giant" RNA and RNA processing: 40 years of enigma / Klaus Scherrer -- The discovery of "split" genes: a scientific revolution / J.A Witkowski -- The In Vitro biosynthesis of an authentic proteIn / Norton D. Zinder -- Early days of Ribosome research / Masayasu Nomura -- The discovery of polyribosomes / Jonathan R. Warner and Paul M. Knopf -- Peptidyl transfer, the Monro era / B. Edward H. Maden -- Forty years under the central dogma / Denis Thieffry and Sahotra Sarkar -- Protein sequencing and the making of molecular genetics / Soraya de Chadarevian -- pBR322 and the advent of rapid DNA sequencing / J. Gregor Sutcliffe -- Biochemisty strickes back / Sydney Brenner ER -