Helmreich, Ernst J.M.

The biochemistry of cell signalling/ Ernst J.M. Helmreich. - 1st ed. - New Delhi: Oxford University Press, 2007. - 328p.: ill.; 24 cm.

Part 1 The machinery of signal transduction
1 Molecular basis of signal transduction
2 Activation of receptors by oligomerization
3 Components of signalling networks: linkers and regulators
4 Signal transduction pathways through small monomeric G proteins
5 Signal transduction pathways through heterotrimeric G proteins: transmission of hormonal and sensory signals
6 Signal transduction pathways controlling morphogensis and haematopoiesis
7 Control of signalling by phosphorylation and dephosphorylation
8 Regulation by a hormone: the insulin response

Part 2 Cell signalling and gene transcription
9 Machinery of gene transcription
10 Regulation of gene transcription by growth factors and cytokines
11 Regulation of gene transcription by hormones

Part 3 Global cell regulatory programmes
12 Regulation of the cell cycle
13 Regulation of cell death
14 Regulation of the immune response

Part 4 Loss of the regulatory control and its consequences
15 Transformation of normal cells to tumor cells
16 Loss of developmental controls in cancer
17 The causes of cancer

9780195673845


Cellular Signal Transduction

574.19 / HEL/T