The biochemistry of cell signalling/
Ernst J.M. Helmreich.
- 1st ed.
- New Delhi: Oxford University Press, 2007.
- 328p.: ill.; 24 cm.
Part 1 The machinery of signal transduction 1 Molecular basis of signal transduction 2 Activation of receptors by oligomerization 3 Components of signalling networks: linkers and regulators 4 Signal transduction pathways through small monomeric G proteins 5 Signal transduction pathways through heterotrimeric G proteins: transmission of hormonal and sensory signals 6 Signal transduction pathways controlling morphogensis and haematopoiesis 7 Control of signalling by phosphorylation and dephosphorylation 8 Regulation by a hormone: the insulin response
Part 2 Cell signalling and gene transcription 9 Machinery of gene transcription 10 Regulation of gene transcription by growth factors and cytokines 11 Regulation of gene transcription by hormones
Part 3 Global cell regulatory programmes 12 Regulation of the cell cycle 13 Regulation of cell death 14 Regulation of the immune response
Part 4 Loss of the regulatory control and its consequences 15 Transformation of normal cells to tumor cells 16 Loss of developmental controls in cancer 17 The causes of cancer