TY - BOOK AU - edited by Curiel, David T. AU - Douglas, Joanne T. TI - Adenoviral vectors for gene therapy SN - 9780121995041 U1 - 581.15 PY - 2002/// CY - Amsterdam PB - Academic Press KW - Andovirus KW - Gene Therapy N1 - 1 Adenovirus Structure 2 Biology of Adenovirus Cell Entry 3 Adenovirus Replication 4 Adenoviral Vector Construction I: Mammalian Systems 5 Adenoviral Vector Construction II: Bacterial Systems 6 Propagation of Adenoviral Vectors: Use of PER.C6 Cells 7 Purification of Adenovirus 8 Targeted Adenoviral Vectors I: Transductional Targeting 9 Targeted Adenoviral Vectors II: Transcriptional Targeting 10 Development of Attenuated Replication Competent Adenoviruses (ARCAs) for the treatment of Prostate Cancer 11 Replication-Selective Oncolytic Adenovirus EI-Region Mutants: Virotherapy for Cancer 12 Innate Immune Responses to in Vivo Adenovirus Infection 13 Humoral Immune Response 14 Novel Methods to Eliminate the Immune Response to Adenovirus Gene Therapy 15 High-Capacity "Gutless" Adenoviral Vectors: Technical Aspects and Applications 16 Xenogenic Adenoviral Vectors 17 Hybrid Adenoviral Vectors 18 Utiliity of Adenoviral Vectors in Animal Models of Human Disease I: Cancer 19 Utiltity of Adenoviral Vectors in Animal Models of Human Disease II: Genetic Disease 20 Utility of Adenoviral Vectors in Animal Models of Human Disease III: Acquired Diseases 21 Testing of Adenoviral Vector Gene Transfer Products: FDA Expectations 22 Imaging Adenovirus-Medicated Gene Transfer ER -