TY - BOOK AU - edited by Honjo, Tasuku AU - Alt, Frederick W. AU - Neuberger, Michael TI - Molecular biology of B cells SN - 9780123979339 U1 - 574.88 PY - 2004/// CY - Amsterdam PB - Elsevier KW - Molecular Immunology KW - B Cells KW - Immunoglobulins N1 - 1 Human Immunoglobulin Heavy Chain Locus 2 Immunoglobulin Heavy Chain Genes of Mouse 3 Immunoglobulin K Genes of Human and Mouse 4 Immunoglobulin Lambda (IGL) Genes of Human and Mouse 5 The Mechanisms of V(D) J Recombination 6 Transcription of Immunoglobulin Genes 7 Early B Cell Development to a Mature, Antigen-Sensitive Cell 8 Allelic Exclusion, Isotypic Exclusion, and the Developmental Regulation of V(D) J Recombination 9 The Development of Human B Lymphocytes 10 Developments and Function of B Cell Subsets 11 Structure and Function of B Cell Antigen Receptor Complexes 12 Regulation of Antigen Receptor Signaling by the Co-Receptors, CD19 and CD22 13 The Dynamic Structure of Antibody Responses 14 Dynamics of B Cell Migration to and within Secondary Lymphoid Organs 15 Characteristics of Mucosal B Cells with Emphasis on the Human Secretory Immune System 16 The Cellular Basis of B Cell Memory 17 Immunoglobulin Assembly and Secretion 18 Fc and Complement Responses 19 Regulation of Class Switch Recombination 20 Molecular Mechanisms of Class Switch Recombination 21 Molecular Mechanisms of Hypermutation 22 Selection During Antigen-Driven B Cell Immune Response: The Basis for High Affinity Antibody 23 Chromosomal Translocations in B Cell Leukemias and Lymphomas 24 Classification and Characteristics of Mouse B Cell-Lineage Lymphomas 25 B Cells Producing Pathogenic Autoantibodies 26 Immunodeficiencies Caused by B Cell Defects 27 Diverse Forms of Immunoglobulin Genes in Lower Vertebrates 28 Immunoglobulin Genes and Generation of Antibody Repertoires in Higher Verbebrates: a Key Role for GALT 29 The Zebrafish Immune System 30 The Origin of V(D) J Diversification 31 Antibody Structure and Recognition of Antigen 32 Monoclonal Antibodies from Display Libraries 33 Humanization of Monoclonal Antibodies 34 Human Monoclonal Antibodies from Translocus Mice ER -