Handbook of glycosyltransferases and related genes/ edited by Naoyuki Taniguchi, Koichi Honke, Minoru Fukuda ; co-editors, Henrik Clausen ... [et al.].

Includes bibliographical references and index.

Part 1 Glucosyltransferases.- 1 Beta-1,3-glucosyltransferase (B3GALTL).- 2 Protein O-glucosyltransferases rumi (RUMI).- 3 UDP-glucose:ceramide glucosyltransferase (UGCG).- 4 UDP-glucose:glycoprotein glucosyltransferase 1,2 (UGGT1,2).- Part 2 Galactosyltransferases.- 5 Alpha 1,3-galactosyltransferase 2, pseudogene (A3GALT2P).- 6 Core 1 beta 3Galactosyltransferase (C1GalT1, T-synthase) and its Specific Molecular Chaperone Cosmc (C1GalT1C1).- 7 Glycoprotein alpha 1,3-galactosyltransferase 1, pseudogene (GGTA1P).- 8 UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 (B3GALT6).- 9 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1,2 (B3GALT1,2).- 10 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 (B3GALT4).- 11 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 (B3GALT5).- 12 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (B4GALT1).- 13 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2-6; xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I) (B4GALT2-7).- 14 UDP-Gal:ceramide galactosyltransferase (UGT8).- 15 UDP-Gal:lactosylceramide alpha 1,4-galactosyltransferase (A4GALT).- Part 3 Mannosyltransferases.- 16 Protein O-mannosyl-transferase 1,2 (POMT1,2).- Part 4 N-Acetylglucosaminyltransferases.- 17 Alpha-1,4-N-acetylglucosaminyltransferase (A4GNT).- 18 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 (GCNT3).- 19 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltrasnsferase 1 (GCNT1) (C2GnT-L)and Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltrasnsferase 3 (GCNT4) (C2GnT-T).- 20 Fringe (UDP-GlcNAc: O-fucosylpeptide ss1,3 N-acetylglucosaminyltransferase).- 21 Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (MGAT1).- 22 Mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A,B (MGAT4A,B).- 23 Mannosyl (alpha-1,3[6?]-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative) (MGAT4C).- 24 Mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (MGAT2).- 25 Mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B (MGAT5B).- 26 Mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase (MGAT5).- 27 Mannosyl (beta-1,4-)-glycoprotein beta-1,4-N- acetylglucosaminyltransferase (MGAT3); 1,4-N- Acetylglucosaminyltransferase III (GnT-III, GlcNAc-T III).- 28 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase (GCNT2) (IGnT).- 29 O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) (OGT).- 30 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGNT1).- 31 UDP-GlcNAc: beta-Gal beta1,3-N-acetylglucosaminyltransferase 6 (B3GNT6) (Core 3 synthase, C3GnT).- 32 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1 (B3GNT1), i-enzyme (iGnT).- 33 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 (B3GNT2).- 34 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 (B3GNT3).- 35 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 (B3GNT5, Lc3Cer synthase).- 36 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 (B3GNT7).- 37 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 (B3GNT8).- Part 5 N-Acetylgalactosaminyltransferases.- 38 Beta-1,4 N-acetylgalactosaminyltransferase 1,2 (B4GALNT1,2).- 39 Beta1,3-N-Acetylgalactosaminyltransferase 2 (B3GALNT2).- 40 Beta1,4-N-acetylgalactosaminyltransferase-3 (B4GALNT3) and beta1,4-N-acetylgalactosaminyltransferase-4 (B4GALNT4).- 41 Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (GBGT1).- 42 Histo-blood Group A and B Transferases, Their Gene Structures, and Common O Group Gene Structures.- 43 Histo-blood Group A Variants, O Variants, and Their Alleles.- 44 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 (B3GNT4).- 45 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferases (ppGalNAc-Ts).- Part 6 Fucosyltransferases.- 46 Fucosyltransferase 3. GDP-fucose lactosamine 1,3/4-fucosyltransferase. Lea and Leb histo-blood groups (FUT3, Lewis enzyme).- 47 Fucosyltransferase 4. GDP-fucose lactosamine 1,3-fucosyltransferase. Myeloid specific (FUT4).- 48 Fucosyltransferase 5. GDP-fucose lactosamine 3/4-fucosyltransferase (FUT5).- 49 Fucosyltransferase 6. GDP-fucose lactosamine 3-fucosyltransferase (FUT6).- 50 Fucosyltransferase 7. GDP-fucose lactosamine 1,3-fucosyltransferase. Sialyl-Lex specific (FUT7).- 51 Fucosyltransferase 8. GDP-fucose N-glycan core 6-fucosyltransferase (FUT8).- 52 Fucosyltransferase 9. GDP-fucose lactosamine 1,3-fucosyltransferase. Lex specific (FUT9).- 53 Fucosyltransferases 1, 2. GDP-fucose galactoside 2-fucosyltransferases. FUT1 or H blood group, FUT2 or ABH secretor status and Sec1 (FUT1, FUT2, Sec1).- 54 Fucosyltransferases 10, 11. GDP-fucose N-glycan core 1,3-fucosyltransferases (FUT10, FUT11).- 55 Fucosyltransferases 12, 13: Protein O-fucosyltransferases 1 and 2 (POFUT1, POFUT2).- Part 7 Sialyltransferases.- 56 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (ST3GAL1).- 57 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 (ST3GAL2).- 58 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 (ST3GAL3).- 59 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 (ST3GAL4).- 60 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 (ST3GAL5).- 61 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 (ST3GAL6).- 62 ST6 beta-galactoside alpha-2,6-sialyltranferase 1 (ST6GAL1).- 63 ST6 beta-galactoside alpha-2,6-sialyltranferase 2 (ST6GAL2).- 64 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (ST6GALNAC1).- 65 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (ST6GALNAC2).- 66 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 (ST6GALNAC3).- 67 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 (ST6GALNAC4).- 68 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5,6 (ST6GALNAC5,6).- 69 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 (ST8SIA1).- 70 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 (ST8SIA2).- 71 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 (ST8SIA3).- 72 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 (ST8SIA4).- 73 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 (ST8SIA5).- 74 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 (ST8SIA6).- Part 8 Glucuronyltransferases.- 75 Beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P); beta-1,3-glucuronyltransferase 2 (B3GAT1,2).- 76 Beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) (B3GAT3).- Part 9 GAG polymerase and related enzymes.- 77 Chondroitin polymerizing factor, chondroitin polymerizing factor 2, chondroitin sulfate synthase 1,3 (CHPF, CHPF2, CHSY1, CHSY3).- 78 Chondroitin sulfate N-acetylgalactosaminyltransferase 1,2 (CSGALNACT1,2).- 79 Dermatan sulfate epimerases (DSE, DSEL).- 80 Exostoses (multiple)-like 1-3 (EXTL1-3).- 81 Exostosin 1,2(EXT1,2).- 82 Heparin-heparansulfate related GlcA C5-epimerase.- 83 Hyaluronan synthase 1-3 (HAS1-3).- 84 Xylosyltransferase I,II (XYLT1,2).- Part 10 Sulfotransferases.- 85 Carbohydrate sulfotransferase 10 (CHST10).- 86 Carbohydrate (chondroitin 4) sulfotransferase 11-13 (CHST11-13).- 87 Carbohydrate (chondroitin 6) sulfotransferase 3; carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 (CHST3,7).- 88 Carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 (CHST1).- 89 Carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 (CHST14).- 90 Carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 (CHST15).- 91 Carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 (CHST4).- 92 Carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 and 6 (CHST5,6).- 93 Carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2(CHST2).- 94 Galactose-3-O-sulfotransferase 1-4 (GAL3ST1-4).- 95 Heparan sulfate 2-O-sulfotransferase (HS2ST).- 96 Heparan sulfate (glucosamine) 3-O-sulfotransferase 1-6 (HS3ST1-6).- 97 Heparan-sulfate 6-O-sulfotransferase 1-3 (HS6ST1-3).- 98 N-Acetylgalactosamine-4-sulfotransferase-1 (GalNAc-4-ST1, CHST8) and N-Acetylgalactosamine-4-sulfotransferase-2 (GalNAc-4-ST2, CHST9).- 99 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 (NDST1).- 100 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 (NDST2).- 101 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3,4 (NDST3,4).- 102 Uronyl-2-sulfotransferase (UST).- Part 11 Glycosyltransferase-like proteins (inplicated in alpha-dystrogly).- 103 Fukutin and fukutin-related protein (FKRP).- 104 Like-glycosyltransferase; glycosyltransferase-like 1B (LARGE, GYLTL1B).- Part 12 GPI anchor biosynthesis.- 105 Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GlcNAc transferase): A complex comprised of PIGA, PIGC, PIGH, PIGQ, PIGP, PIGY and DPM2.- 106 GPI mannose extension (PIGM, PIGV, PIGB, PIGZ).- Part 13 N-Glycan precursor biosynthesis, en-bloc transfer and processing.- 107 ALG mannosyltransferases, ER lumen = alpha linkage (ALG3,9,12).- 108 Dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) (DPAGT1).- 109 Glucosidase, alpha neutral AB; glucosidase II subunit beta (GANAB, PRKCSH, -glucosidase II).- 110 Heterodimeric Alg13/Alg14 UDP-GlcNAc transferase (ALG13,14).- 111 Mannosidase, alpha, class 1 (MAN1A1 (Golgi alpha-mannnosidase IA), Man1A2 (Golgi alpha-mannosidase IB), MAN1B1(ER alpha-mannosidase I), MAN1C1 (Golgi alpha-mannosidase IC ).- 112 Mannosidase, alpha, class 2a1 (MAN2A1, Golgi -mannosidase II).- 113 Mannosidase, alpha, class 2a2 (MAN2A2).- 114 Mannosyl-oligosaccharide glucosidase (Glucosidase I, MOGS).- 115 N-acetylglucosamine-1-phosphate transferase, gamma subunit; N-acetylglucosamine-1- (GNPTG, GNPTAB).- 116 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (NAGPA).- 117 OST complex (OST48, Ribophorin I, Ribophorin II, DAD1).- 118 The Alg1, Alg2, and Alg11 Mannosyltransferases of the Endoplasmic Reticulum.- Part 14 Nucleotide sugar transporters.- 119 Adenosine 3'-phospho 5'-phosphosulfate transporter 1,2 (PAPST1,2) (SLC35B2,3).- 120 GDP-fucose transporter 1 (SLC35C1).- 121 Solute carrier family 35 (CMP-sialic acid transporter), member A1 (SLC35A1).- 122 Solute carrier family 35 (UDP-galactose transporter), member A2 (SLC35A2).- 123 UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter (HFRC1) (SLC35D2).- 124 UDP-xylose and UDP-N-acetylglucosamine transporter (SLC35B4).- Part 15 Transferase donor substrate biosynthesis and related reactions.- 125 Cytidine monophosphate N-acetylneuraminic acid synthetase (CMAS).- 126 Cytidine monophospho-N-acetylneuraminic acid hydroxylase (CMAH).- 127 Dolichyl-phosphate beta-glucosyltransferase (ALG5).- 128 Dolichyl-phosphate mannosyltransferase polypeptide (DPM1-3).- 129 Fucokinase (FUK).- 130 Fucose-1-phosphate guanylyltransferase (FPGT ).- 131 GDP-mannose pyrophosphorylase A,B (GMPPA,B).- 132 Glucosamine-6 phosphate N-acetyltransferase (GNPNAT1 / GNA1).- 133 Glutamine--fructose-6-phosphate transaminase 1,2 (GFPT1,2).- 134 Mannose phosphate isomerase (MPI).- 135 N-acetylglucosamine kinase (NAGK).- 136 N-acetylneuraminic acid phosphatase (NANP).- 137 N-acetylneuraminic acid synthase (NANS).- 138 Phosphoglucomutase 3 (= phosphoacetylglucosamine mutase) (PGM3).- 139 Phosphomannomutase 1,2 (PMM1,2).- 140 Tissue specific transplantation antigen P35B (= GDP-4-keto-6-D-deoxymannose epimerase-reductase) (TSTA3).- 141 UDP-galactose-4-epimerase (GALE).- 142 UDP-GlcNAc-2-epimerase/ManNAc kinase (GNE).- 143 UDP-glucose 6-dehydrogenase (UGDH).- 144 UDP-glucuronate decarboxylase 1 (UXS1).- 145 UDP-N-acteylglucosamine pyrophosphorylase 1 (UAP1).- BM Appendix.- Map 1: Biosynthetic Pathways of N-Glycans.- Map 2: Biosynthetic Pathways of O-Glycans.- Map 3: Biosynthetic Pathways of Glycosphingolipids.- Map 4: Biosynthetic Pathways of Proteoglycans.- Map 5: Biosynthetic Pathways of GPI-Anchor.