Comprehensive biotechnology Vol. 3/ (Record no. 180139)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 00387nam a2200121Ia 4500 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CUS |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 660.6 |
| Item number | MOO/C |
| 245 #0 - TITLE STATEMENT | |
| Title | Comprehensive biotechnology Vol. 3/ |
| Sub title | principles and practices in industry agriculture medicine and the environment |
| Statement of responsibility, etc. | Moo-Young,Murray |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication, distribution, etc. | Amsterdam: |
| Name of publisher, distributor, etc. | Elsevier, |
| Date of publication, distribution, etc. | 2011. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 690 |
| 505 ## - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 3.01. Introduction<br/><br/>Acknowledgments<br/><br/>3.02. Industrial Enzymes<br/><br/>Glossary<br/><br/>3.02.1. Introduction<br/><br/>3.02.2. Protease<br/><br/>3.02.3. Lipase<br/><br/>3.02.4. Amylase<br/><br/>3.02.5. Pullulanases<br/><br/>3.02.6. Pectinases<br/><br/>3.02.7. Xylanase<br/><br/>3.02.8. Laccases<br/><br/>3.02.9. Transglutaminases<br/><br/>3.02.10. Phytase<br/><br/>3.02.11. Perspective<br/><br/>3.03. Multifunctional Enzyme Systems for Plant Cell Wall Degradation<br/><br/>Glossary<br/><br/>Acknowledgments<br/><br/>3.03.1. Introduction<br/><br/>3.03.2. Diversity of Multifunctional Enzymes<br/><br/>3.03.3. Inter- and Intra Molecular Synergism<br/><br/>3.03.4. Intra Molecular Synergism: Clues from Three-Dimensional Structures<br/><br/>3.03.5. Artificial Chimeras<br/><br/>3.03.6. Future Perspective<br/><br/>3.04. Ethanol Production from Sugar-Based Feedstocks<br/><br/>Glossary<br/><br/>3.04.1. Introduction<br/><br/>3.04.2. Feedstocks<br/><br/>3.04.3. Land Availability Scenarios<br/><br/>3.04.4. Feedstock Processing for Ethanol<br/><br/>3.04.5. Conclusions<br/><br/>3.05. Ethanol from Starch-Based Feedstocks<br/><br/>Glossary<br/><br/>3.05.1. Introduction<br/><br/>3.05.2. Biochemistry of the Ethanol Process<br/><br/>3.05.3. Yeasts Used in the Process<br/><br/>3.05.4. Unit Operations Relevant to Ethanol Production<br/><br/>3.05.5. Environmental Requirements in Fermentation<br/><br/>3.05.6. Yield Coefficient and Net Rate Expression<br/><br/>3.05.7. Metabolic Flux Analysis<br/><br/>3.05.8. Summary<br/><br/>3.06. Biofuels from Cellulosic Feedstocks<br/><br/>Glossary<br/><br/>3.06.1. Introduction<br/><br/>3.06.2. Cellulosic Biomass<br/><br/>3.06.3. Conversion of Cellulosic Biomass into Ethanol<br/><br/>3.06.4. Development of Microorganisms for Fermenting Cellulosic Biomass Hydrolyzates to Ethanol<br/><br/>3.06.5. Conclusions<br/><br/>3.07. Biodiesel<br/><br/>Glossary<br/><br/>3.07.1. Introduction<br/><br/>3.07.2. Pyrolysis or Thermal Cracking<br/><br/>3.07.3. Microemulsions<br/><br/>3.07.4. Transesterification – Conventional Methods<br/><br/>3.07.5. Transesterification – Supercritical Fluids<br/><br/>3.07.6. Transesterification – Enzymatic<br/><br/>3.07.7. Nonedible Oils as Potential Substrates<br/><br/>3.07.8. Packed-Bed Reactors Containing Whole-Cell Biocatalysts<br/><br/>3.07.9. Conclusion and Future Prospects<br/><br/>3.08. Biofuels and Bioenergy<br/><br/>Glossary<br/><br/>3.08.1. Introduction<br/><br/>3.08.2. History<br/><br/>3.08.3. Microorganisms<br/><br/>3.08.4. Metabolic Pathway of Acetone and Butanol Formation<br/><br/>3.08.5. Genetic Engineering<br/><br/>3.08.6. Systems Biology<br/><br/>3.08.7. Fermentation<br/><br/>3.08.8. Development of Fermentation Technology<br/><br/>3.09. Microbial Production of 2,3-Butanediol<br/><br/>Glossary<br/><br/>3.09.1. Introduction<br/><br/>3.09.2. Properties and Applications of 2,3-Butanediol<br/><br/>3.09.3. Microorganisms Producing 2,3-Butanediol<br/><br/>3.09.4. Metabolic Pathway and Pathway Engineering<br/><br/>3.09.5. Fermentation of 2,3-Butanediol<br/><br/>3.09.6. Recovery of 2,3-Butanediol<br/><br/>3.09.7. Summary and Future Prospects<br/><br/>3.10. Biogas<br/><br/>Glossary<br/><br/>3.10.1. Introduction<br/><br/>3.10.2. Fundamentals<br/><br/>3.10.3. AD Process<br/><br/>3.10.4. Application of Biogas Technology<br/><br/>3.10.5. Utilization of Biogas<br/><br/>3.10.6. Perspectives<br/><br/>3.11. Biohydrogen<br/><br/>Glossary<br/><br/>3.11.1. Introduction<br/><br/>3.11.2. Biophotolysis of Water<br/><br/>3.11.3. Photofermentation by Photosynthetic Bacteria<br/><br/>3.11.4. Dark Fermentation<br/><br/>3.11.5. CO Gas Fermentation<br/><br/>3.11.6. Closing Remarks<br/><br/>3.12. Biofuel from Microalgae<br/><br/>Glossary<br/><br/>3.12.1. Introduction and Scope<br/><br/>3.12.2. Major Algal Composition<br/><br/>3.12.3. Different Types of Biofuels from Microalgae<br/><br/>3.12.4. Algal Biodiesel Production Pipeline<br/><br/>3.12.5. Conclusion and Perspectives<br/><br/>3.13. Citric Acid<br/><br/>Glossary<br/><br/>3.13.1. Introduction and Scope<br/><br/>3.13.2. Properties and Applications of Citric Acid<br/><br/>3.13.3. Historical Background of Citric Acid Production<br/><br/>3.13.4. Microorganisms and Biosynthesis of Citric Acid<br/><br/>3.13.5. Factors Affecting Citric Acid Production by A. niger<br/><br/>3.13.6. Fermentation Processes for Citric Acid Production<br/><br/>3.13.7. Product Recovery<br/><br/>3.13.8. Perspectives for the Future<br/><br/>3.14. Gluconic and Itaconic Acids<br/><br/>Glossary<br/><br/>3.14.1. Introduction and Scope<br/><br/>3.14.2. d-Gluconic Acid<br/><br/>3.14.3. Itaconic Acid<br/><br/>3.14.4. Perspectives for Future<br/><br/>3.15. Organic Acids<br/><br/>Glossary<br/><br/>Acknowledgments<br/><br/>3.15.1. Introduction<br/><br/>3.15.2. Succinic Acid Production<br/><br/>3.15.3. Use of Succinic Acid and Its Derivatives<br/><br/>3.15.4. Malic Acid Production<br/><br/>3.15.5. Malic Acid and Its Applications<br/><br/>3.15.6. Conclusion<br/><br/>3.16. Fumaric Acid<br/><br/>Glossary<br/><br/>Acknowledgments<br/><br/>3.16.1. Introduction<br/><br/>3.16.2. Properties and Applications<br/><br/>3.16.3. Industrial Production Methods<br/><br/>3.16.4. Fumaric Acid Fermentation Microbiology<br/><br/>3.16.5. Fermentation Process Development and Optimization<br/><br/>3.16.6. Conclusion and Future Prospects<br/><br/>3.17. Industrial Production of Lactic Acid<br/><br/>Glossary<br/><br/>3.17.1. Introduction<br/><br/>3.17.2. General Characteristics of Lactic Acid<br/><br/>3.17.3. Biological Production of Lactic Acid<br/><br/>3.17.4. The Cargill Yeast<br/><br/>3.17.5. Fermentation Carbon Sources<br/><br/>3.17.6. Purification of Lactic Acid from Fermentation Broth<br/><br/>3.17.7. An Emergent Commercial Application of Lactic Acid: PLA<br/><br/>3.18. Acetic and Propionic Acids<br/><br/>Glossary<br/><br/>Acknowledgments<br/><br/>3.18.1. Introduction<br/><br/>3.18.2. Properties and Applications of Acetic and Propionic Acids<br/><br/>3.18.3. Microbiology of Acetic Acid Fermentation<br/><br/>3.18.4. Product Recovery and Purification<br/><br/>3.18.5. Summary<br/><br/>3.19. Acrylic Acid<br/><br/>Glossary<br/><br/>Acknowledgments<br/><br/>3.19.1. Introduction<br/><br/>3.19.2. Process Development<br/><br/>3.19.3. Proposed Novel Biosynthetic Pathways and Industrial Production Process<br/><br/>3.19.4. Summary<br/><br/>3.20. Butyric Acid<br/><br/>Glossary<br/><br/>Acknowledgments<br/><br/>3.20.1. Introduction<br/><br/>3.20.2. Properties and Uses of Butyric Acid<br/><br/>3.20.3. Fermentation of Butyric Acid<br/><br/>3.20.4. Fundamentals and Molecular Manipulation<br/><br/>3.20.5. Product Recovery<br/><br/>3.20.6. Summary<br/><br/>3.21. PHA/PHB<br/><br/>Glossary<br/><br/>3.21.1. Introduction<br/><br/>3.21.2. Production of PHA/PHB by Wild-Type Microorganisms<br/><br/>3.21.3. PHA Production by Metabolically Engineered Microorganisms<br/><br/>3.21.4. Applications of PHA/PHB<br/><br/>3.22. 1,3-Propanediol and Polytrimethyleneterephthalate<br/><br/>Glossary<br/><br/>3.22.1. Introduction<br/><br/>3.22.2. Polytrimethyleneterephthalate<br/><br/>3.22.3. Properties and Uses of PDO<br/><br/>3.22.4. Metabolic Pathways and Engineering of PDO Formation<br/><br/>3.22.5. Fermentation Conditions and Operation Modes<br/><br/>3.22.6. Recovery and Purification of PDO<br/><br/>3.22.7. Production Costs and Biorefinery Concept<br/><br/>3.22.8. Conclusion and Perspectives<br/><br/>3.23. Antibiotics<br/><br/>Glossary<br/><br/>3.23.1. Introduction<br/><br/>3.23.2. The Miracle of Antibiotics<br/><br/>3.23.3. The Golden Era of Antibiotic Discovery<br/><br/>3.23.4. Microbial Genomics and the Failure of Antibiotic Discovery Research<br/><br/>3.23.5. Medical Need, Antimicrobial Resistance, and the Anti-Infective Marketplace<br/><br/>3.23.6. The Regulatory Environment for Antibacterials<br/><br/>3.23.7. Large Pharmaceutical Companies Exit and Biotechnology Enters<br/><br/>3.23.8. Conclusions<br/><br/>3.24. Penicillins and Cephalosporins<br/><br/>Glossary<br/><br/>3.24.1. Introduction to Penicillins and Cephalosporins<br/><br/>3.24.2. Structure and Mechanism of Action of Penicillins and Cephalosporins<br/><br/>3.24.3. Penicillin and Cephalosporin Biosynthesis<br/><br/>3.24.4. Biotechnological Implications in the Biosynthesis of Penicillins and Cephalosporins<br/><br/>3.24.5. Future Outlook<br/><br/>3.25. Tetracyclines and Tetracycline Derivatives<br/><br/>Glossary<br/><br/>3.25.1. Introduction and Scope<br/><br/>3.25.2. Tetracycline Generations and Origins<br/><br/>3.25.3. First-Generation Tetracyclines<br/><br/>3.25.4. Antibacterial Uses of the Tetracyclines<br/><br/>3.25.5. First- and Second-Generation Tetracyclines and Their Semisynthetic Modifications<br/><br/>3.25.6. Semisynthesis of Third-Generation Tetracyclines: Derivatives of Minocycline, Sancycline, and Doxycycline<br/><br/>3.25.7. Tetracycline Antibacterial Quantitative Structure-Activity Relationships (QSAR)<br/><br/>3.25.8. Antibacterial and General Chemical Properties of the Tetracyclines: Uptake and Membrane Activity<br/><br/>3.25.9. Mechanism of Action and Antibacterial Activity<br/><br/>3.25.10. Conclusions<br/><br/>3.26. Microbial Secondary Metabolites<br/><br/>Glossary<br/><br/>3.26.1. Introduction<br/><br/>3.26.2. Source of Bioactive Microbial Secondary Metabolites<br/><br/>3.26.3. Overview of Bioactivities<br/><br/>3.26.4. Microbial Product Screening<br/><br/>3.26.5. Production Processes<br/><br/>3.26.6. Examples of Successful Secondary Metabolites<br/><br/>3.26.7. Conclusions<br/><br/>3.27. Plant Secondary Metabolites<br/><br/>Glossary<br/><br/>Acknowledgments<br/><br/>3.27.1. Plants and Secondary Metabolites<br/><br/>3.27.2. Heterogeneity of Plant Secondary Metabolites<br/><br/>3.27.3. Secondary Metabolite Production by Plant Cell Culture<br/><br/>3.27.4. Signal Transduction Engineering for Enhancing Secondary Metabolite Production<br/><br/>3.27.5. Modulation of Secondary Metabolic Pathway<br/><br/>3.27.6. Conclusions and Perspectives<br/><br/>3.28. Biocatalyzed Production of Fine Chemicals<br/><br/>Glossary<br/><br/>3.28.1. Introduction<br/><br/>3.28.2. Preparation of Fine Chemicals from Renewable Raw Materials<br/><br/>3.28.3. Whole Cell-Catalyzed Synthesis of Fine Chemicals<br/><br/>3.28.4. Enzyme-Catalyzed Production of Fine Chemicals<br/><br/>3.29. Production of Recombinant Proteins by Microbes and Higher Organisms<br/><br/>Glossary<br/><br/>3.29.1. Introduction<br/><br/>3.29.2. Enzyme Production<br/><br/>3.29.3. Systems for Producing Recombinant Proteins<br/><br/>3.29.4. Conclusions<br/><br/>3.30. Vaccines<br/><br/>Glossary<br/><br/>3.30.1. Introduction<br/><br/>3.30.2. Smallpox Vaccine and Other Vaccines of the Nineteenth Century<br/><br/>3.30.3. The Importance of Vaccines<br/><br/>3.30.4. Milestones in Vaccine Technology<br/><br/>3.31. Manufacturing Recombinant Proteins in kg-ton Quantities Using Animal Cells in Bioreactors<br/><br/>Glossary<br/><br/>3.31.1. Introduction<br/><br/>3.31.2. Generation of CHO-Derived Cell Lines<br/><br/>3.31.3. Improved Recovery of High-Producing Cell Lines<br/><br/>3.31.4. High-Throughput Bioprocess Development<br/><br/>3.31.5. Disposable Bioreactors<br/><br/>3.31.6. Transient Gene Expression<br/><br/>3.31.7. Conclusions<br/><br/>3.32. Recent and Emerging Trends and Concerns Related to the Manufacturing and Testing of Monoclonal Antibodies Intended for Clinical Use<br/><br/>Glossary<br/><br/>3.32.1. Introduction<br/><br/>3.32.2. Characterization of mAb Quality Attributes<br/><br/>3.32.3. QbD/Design Space<br/><br/>3.32.4. New and Emerging Antibody-Related Products<br/><br/>3.32.5. Engineering Enhanced mAb Domain Functionality<br/><br/>3.32.6. Emerging Product Quality Concerns<br/><br/>3.32.7. Comparability Considerations<br/><br/>3.32.8. New Analytics<br/><br/>3.32.9. Platform Technologies<br/><br/>3.32.10. Emerging Chemistry, Manufacturing and Controls Technology<br/><br/>3.32.11. Conclusion<br/><br/>3.33. Therapeutic Enzymes and Biomimetic Substrates<br/><br/>Glossary<br/><br/>3.33.1. Introduction<br/><br/>3.33.2. Nomenclature<br/><br/>3.33.3. Enzyme Kinetics<br/><br/>3.33.4. Substrate Considerations<br/><br/>3.33.5. Complex Heterodisperse Natural Substrates<br/><br/>3.33.6. Application of Cell-Based Activity Assays to Qualification of Non-Biomimetic Substrates<br/><br/>3.33.7. Conclusions<br/><br/>3.34. Cell-Free Production of Pharmaceutical Proteins<br/><br/>Glossary<br/><br/>3.34.1. Introduction<br/><br/>3.34.2. Types of Cell-Free Systems<br/><br/>3.34.3. Advantages of Cell-Free Protein Production<br/><br/>3.34.4. Challenges with Cell-Free Protein Production<br/><br/>3.34.5. Small-Scale Applications<br/><br/>3.34.6. Novel Pharmaceutical Product Opportunities<br/><br/>3.34.7. Large-Scale Considerations<br/><br/>3.34.8. Summary<br/><br/>3.35. Combination Products Are Not Solely Biological Products, Drugs, or Devices<br/><br/>Glossary<br/><br/>Acknowledgment<br/><br/>3.35.1. Introduction and Definitions<br/><br/>3.35.2. FDA’s Organization and the Office of Combination Products<br/><br/>3.35.3. Request for Designation, Primary Mode of Action, and Assignment of Jurisdiction<br/><br/>3.35.4. How Things Work – Differences in Processes between Centers<br/><br/>3.35.5. How Things Work – Similarities in Processes between Centers<br/><br/>3.35.6. The Future<br/><br/>3.35.7. Conclusions<br/><br/>3.36. Cellular Therapies<br/><br/>Glossary<br/><br/>3.36.1. Introduction<br/><br/>3.36.2. Sources of Cells and Clinical Applications of Cell Therapy<br/><br/>3.36.3. Cell-Based Products for Reconstructive or Structural Repair<br/><br/>3.36.4. Cellular Vaccines<br/><br/>3.36.5. Adoptive Cell Therapies<br/><br/>3.36.6. Stem Cell-Derived Therapies<br/><br/>3.36.7. Cell Isolation and Processing Methods<br/><br/>3.36.8. Summary<br/><br/>3.37. Gene Therapies<br/><br/>Glossary<br/><br/>3.37.1. Introduction and Scope<br/><br/>3.37.2. Current Status of Gene Therapy Products in Commerce and Clinical Development<br/><br/>3.37.3. Challenges Pertinent to the Development of Gene Therapy Products<br/><br/>3.37.4. Regulatory Issues and Standardization Activities Pertinent to Gene Therapy Products<br/><br/>3.37.5. Manufacturing of Gene Therapy Products<br/><br/>3.37.6. Vectors Employed in Gene Therapy Products<br/><br/>3.37.7. Manufacturing and Purification Strategies<br/><br/>3.37.8. Product Characterization<br/><br/>3.37.9. Process Validation<br/><br/>3.37.10. Product Administration of Gene Therapy Products<br/><br/>3.37.11. Conclusion<br/><br/>3.38. Regulatory Aspects of Chemistry Manufacturing and Controls for Investigational New Drug Applications and Biologic License Applications to the United States Food and Drug Administration<br/><br/>Glossary<br/><br/>3.38.1. Introduction<br/><br/>3.38.2. IND Applications<br/><br/>3.38.3. Biologic License Application<br/><br/>3.38.4. Comparability Testing<br/><br/>3.38.5. Communication with the FDA from Pre-IND through Licensure<br/><br/>3.38.6. Conclusions<br/><br/>3.39. Raw Materials in the Manufacture of Biotechnology Products<br/><br/>Glossary<br/><br/>3.39.1. Introduction: Raw Materials in the Biotechnology Industry<br/><br/>3.39.2. Regulations on Raw Materials<br/><br/>3.39.3. Considerations on Raw Materials<br/><br/>3.39.4. Impact of the Quality of the Raw Material on the Quality of the Final Biotechnology Product<br/><br/>3.39.5. Control of the Quality of Raw Materials<br/><br/>3.39.6. Life Cycle of a Raw Material in Biotechnology Products<br/><br/>3.39.7. Management of Raw Materials in the Context of ICH Guidelines<br/><br/>3.39.8. Controlling the Risk of Introducing Raw Materials<br/><br/>3.39.9. Future Directions<br/><br/>3.40. Characterization of Biotechnological/Biological/Biosimilar Products<br/><br/>Glossary<br/><br/>3.40.1. Assessment of Product Characteristics<br/><br/>3.40.2. Biotechnology Product Characterization, Comparability, Release, and Stability Tool Kits<br/><br/>3.40.3. Selection of Analytical Methods<br/><br/>3.40.4. Analytical Method Lifecycle Issues<br/><br/>3.40.5. Conclusions<br/><br/>3.41. Protein Glycosylation<br/><br/>Glossary<br/><br/>3.41.1. Introduction<br/><br/>3.41.2. Analysis of Intact Glycoproteins and Glycopeptides<br/><br/>3.41.3. Analysis of Free Glycans<br/><br/>3.41.4. Analysis of Monosaccharides<br/><br/>3.41.5. Glycan Analysis Design for Therapeutic Glycoproteins<br/><br/>3.42. Immunogenicity Assay Development and Validation<br/><br/>Glossary<br/><br/>3.42.1. Introduction<br/><br/>3.42.2. Development of Binding Antibody Methods<br/><br/>3.42.3. Validation of Binding Antibody Methods<br/><br/>3.42.4. Development of NAb Methods<br/><br/>3.42.5. Validation of NAb Methods<br/><br/>3.42.6. Practical Considerations and Recommendations<br/><br/>3.42.7. Concluding Remarks<br/><br/>3.43. Process Analytical Technology in Bioprocess Development and Manufacturing<br/><br/>Glossary<br/><br/>3.43.1. Introduction and Scope<br/><br/>3.43.2. PAT Tools<br/><br/>3.43.3. Concluding Remarks<br/><br/>3.44. Process Validation<br/><br/>Glossary<br/><br/>3.44.1. Introduction and Scope<br/><br/>3.44.2. General Requirements and Considerations<br/><br/>3.44.3. Process Knowledge<br/><br/>3.44.4. Validation of the Commercial Process<br/><br/>3.45. Follow-On Protein Products<br/><br/>Glossary<br/><br/>3.45.1. Introduction<br/><br/>3.45.2. Unique challenges associated with protein products<br/><br/>3.45.3. Impact of the manufacturing process on product quality<br/><br/>3.45.4. Impact of product quality on clinical performance<br/><br/>3.45.5. Conclusions<br/><br/>3.46. Amino Acid Production<br/><br/>Glossary<br/><br/>3.46.1. Introduction<br/><br/>3.46.2. Microbial Production<br/><br/>3.46.3. Enzymatic Production<br/><br/>3.46.4. Future Prospects<br/><br/>3.47. Lysine<br/><br/>Glossary<br/><br/>Acknowledgment<br/><br/>3.47.1. Introduction<br/><br/>3.47.2. Biological Properties and Applications of d-Lysine, ε-Poly-l-Lysine, and l-Lysine<br/><br/>3.47.3. History of Industrial l-Lysine Production<br/><br/>3.47.4. Different Commercial Production Methods for l-Amino Acids<br/><br/>3.47.5. Fermentation Is the Dominant Method for Industrial l-Lysine Production<br/><br/>3.47.6. The l-Lysine Biosynthetic Pathway from Aspartate<br/><br/>3.47.7. Metabolic Engineering of C. glutamicum for l-Lysine Overproduction<br/><br/>3.47.8. Alternative Raw Materials and Production Strains for l-Lysine Production<br/><br/>3.47.9. Conclusions and Perspectives<br/><br/>3.48. Food-Grade Enzymes<br/><br/>Glossary<br/><br/>Acknowledgments<br/><br/>3.48.1. Introduction<br/><br/>3.48.2. Sources of Food-Grade Enzymes<br/><br/>3.48.3. Food-Grade Enzymes Targeted at Processing<br/><br/>3.48.4. Food-Grade Enzymes Targeted at Preservation<br/><br/>3.48.5. Production of Food-Grade Enzymes<br/><br/>3.48.6. Recovery of Food-Grade Enzymes<br/><br/>3.48.7. Polishing of Food-Grade Enzymes<br/><br/>3.48.8. Safety Concerns with Food-Grade Enzymes<br/><br/>3.49. Proteases<br/><br/>Glossary<br/><br/>3.49.1. Introduction<br/><br/>3.49.2. Protease Types<br/><br/>3.49.3. Principal Industrial Sources/Production Processes<br/><br/>3.49.4. Principal Applications of Proteases<br/><br/>3.49.5. Protease Inhibitors<br/><br/>3.50. Application of Enzymes and Microbes for the Industrial Production of Vitamins and Vitamin-Like Compounds<br/><br/>Glossary<br/><br/>3.50.1. Introduction and Scope<br/><br/>3.50.2. Riboflavin – Vitamin B2<br/><br/>3.50.3. Niacin – Vitamin B3<br/><br/>3.50.4. R-Pantothenic Acid and R-Panthenol – Vitamin B5 and Provitamin B5<br/><br/>3.50.5. Biotin – Vitamin B7<br/><br/>3.50.6. Cobalamin – Vitamin B12<br/><br/>3.50.7. l-Ascorbic Acid – Vitamin C<br/><br/>3.50.8. Phylloquinones and Menaquinones – Vitamin K<br/><br/>3.50.9. Coenzyme Q10<br/><br/>3.50.10. Pyrroloquinoline Quinone<br/><br/>3.50.11. l-Carnitine<br/><br/>3.50.12. Outlook<br/><br/>3.51. Fungal Biotechnology in Food and Feed Processing<br/><br/>Glossary<br/><br/>3.51.1. Introduction<br/><br/>3.51.2. Use of Fungi in Dietary Food<br/><br/>3.51.3. Use of Fruiting Body<br/><br/>3.51.4. Fungi as and in Processed Food<br/><br/>3.51.5. Processed Fungal Food as an Alternative to SCPs<br/><br/>3.51.6. Use of Enzymes in Food and Feed Bioprocessing<br/><br/>3.51.7. Fungal Enzymes Used in Feed<br/><br/>3.51.8. Commercial Recombinant Enzymes from Fungi<br/><br/>3.51.9. Secondary Metabolites from Fungi used in Food and Feed<br/><br/>3.51.10. Pharmaceutical and Nutraceutical Byproducts from Fungi<br/><br/>3.51.11. Symbiotic Fungus Termitomyces: A Filamentous Basidiomycota<br/><br/>3.51.12. Termitomyces clypeatus: An Edible Fungus and Producer of Enzymes<br/><br/>3.51.13. Bioprocessing of Food by T. clypeatus<br/><br/>3.51.14. Concluding Remarks and Future Prospects<br/><br/>3.52. Metabolic Engineering<br/><br/>Glossary<br/><br/>3.52.1. Introduction: Evolution of Metabolic Engineering<br/><br/>3.52.2. Biological Systems<br/><br/>3.52.3. Desired Products<br/><br/>3.52.4. Engineering Strategies<br/><br/>3.52.5. Future Perspectives<br/><br/>3.53. Synthetic Biology<br/><br/>Glossary<br/><br/>3.53.1. Introduction<br/><br/>3.53.2. Historical Foundation<br/><br/>3.53.3. Foundational Research and Development<br/><br/>3.53.4. Enabling Technologies<br/><br/>3.53.5. Research and Education<br/><br/>3.53.6. Applications of Synthetic Biology<br/><br/>3.53.7. Regulatory Debate<br/><br/>3.53.8. Synbioethics<br/><br/>3.53.9. Intellectual Property<br/><br/>3.53.10. Looking Ahead<br/><br/>3.54. Industrial Biotechnology and Commodity Products<br/><br/>Glossary<br/><br/>3.54.1. Introduction<br/><br/>3.54.2. Upstream Activities<br/><br/>3.54.3. Downstream Activities<br/><br/>3.54.4. General Components<br/><br/>3.54.5. Future Designs and Facility Layouts<br/><br/>3.55. Bioreactors for Commodity Products<br/><br/>Glossary<br/><br/>3.55.1. Introduction<br/><br/>3.55.2. Classifications of Bioreactors<br/><br/>3.55.3. Types of Bioreactors<br/><br/>3.55.4. Bioreactors and Sustainability<br/><br/>3.56. Integrating Process Scouting Devices (PSDs) With Bench-Scale Devices<br/><br/>Glossary<br/><br/>3.56.1. Introduction<br/><br/>3.56.2. Process Scouting Devices Challenges<br/><br/>3.56.3. Integrating PSDs with Bench-Scale Devices by Developing a Scale-Up Strategy<br/><br/>3.56.4. Types of Process Scouting Devices<br/><br/>3.56.5. Future Developments<br/><br/>3.56.6. Conclusion<br/><br/>3.57. Overview of Downstream Processing in the Biomanufacturing Industry<br/><br/>Glossary<br/><br/>3.57.1. Introduction and Scope<br/><br/>3.57.2. Principles of DSP<br/><br/>3.57.3. Clarification Methods in DSP<br/><br/>3.57.4. Chromatography for Product Capture and Polishing<br/><br/>3.57.5. Filtration Methods Used in Product Purification and Formulation<br/><br/>3.57.6. Crystallization as a Low-Technology Polishing Method<br/><br/>3.57.7. Current Trends in the Biomanufacturing Industry<br/><br/>3.58. Nanotechnology<br/><br/>Glossary<br/><br/>3.58.1. Introduction<br/><br/>3.58.2. Types of Nanotechnology<br/><br/>3.58.3. Bionanotechnology and Nanobiotechnology<br/><br/>3.58.4. Nanotechnology at the Biological Interface<br/><br/>3.59. Biosurfactants<br/><br/>Glossary<br/><br/>3.59.1. Introduction<br/><br/>3.59.2. General Aspects<br/><br/>3.59.3. Applications<br/><br/>3.59.4. Perspectives and Future Development<br/><br/>3.59.5. Perspectives for Future Development<br/><br/>3.60. Bioleaching and Biomining for the Industrial Recovery of Metals<br/><br/>Glossary<br/><br/>3.60.1. Introduction<br/><br/>3.60.2. Microorganisms Involved in Biomining<br/><br/>3.60.3. Industrial Biomining of Ores<br/><br/>3.60.4. Environmental Impact of Biomining Activities<br/><br/>3.60.5. Microbial Metal Solubilization Mechanisms<br/><br/>3.60.6. Importance of Molecular Biology Studies in Metal Extraction<br/><br/>3.60.7. Perspectives<br/><br/>3.61. Biological Control<br/><br/>Glossary<br/><br/>3.61.1. Introduction<br/><br/>3.61.2. Biological Control<br/><br/>3.61.3. Biopesticides Classification<br/><br/>3.61.4. Biopesticide Categories<br/><br/>3.61.5. Biological Control of Aflatoxin Contamination of Crops<br/><br/>3.61.6. Use of Genetic-Engineering Technology<br/><br/>3.61.7. Engineering Biological Control Agents<br/><br/>3.61.8. Integrated Pest Management<br/><br/>3.61.9. Market<br/><br/>3.61.10. Conclusion |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Reference Books |
| Withdrawn status | Lost status | Damaged status | Not for loan | Collection Type | Home library | Current library | Shelving location | Date acquired | Full call number | Accession number | Date last seen | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Not For Loan | Reference Collection | Central Library, Sikkim University | Central Library, Sikkim University | Reference | 29/08/2016 | 660.6 MOO/C | P35151 | 23/09/2022 | Reference Books |