Comprehensive biotechnology Vol. 1/ (Record no. 180137)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 00387nam a2200121Ia 4500 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CUS |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 660.6 |
| Item number | MOO/C |
| 245 #0 - TITLE STATEMENT | |
| Title | Comprehensive biotechnology Vol. 1/ |
| Sub title | principles and practices in industry agriculture medicine and the environment |
| Statement of responsibility, etc. | Moo-Young,Murray |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication, distribution, etc. | Amsterdam: |
| Name of publisher, distributor, etc. | Elsevier, |
| Date of publication, distribution, etc. | 2011. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 690 |
| 505 ## - FORMATTED CONTENTS NOTE | |
| Formatted contents note | General Preface<br/><br/>Nomenclature Guidelines<br/><br/>Permission Acknowledgments<br/><br/>1.01. Introduction<br/><br/>1.02. Amino Acid Metabolism<br/><br/>Glossary<br/><br/>1.02.1. Introduction<br/><br/>1.02.2. General Properties, Classification, and Structure of Amino Acids<br/><br/>1.02.3. Biosynthesis of Amino Acids<br/><br/>1.02.4. Catabolism of Amino Acids<br/><br/>1.02.5. Important Biomolecules Synthesized from Amino Acids<br/><br/>1.03. Enzyme Biocatalysis<br/><br/>Glossary<br/><br/>1.03.1. Introduction to Enzymes<br/><br/>1.03.2. Enzyme Kinetics<br/><br/>1.03.3. Enzyme Engineering<br/><br/>1.03.4. Enzyme Production<br/><br/>1.03.5. Immobilized Enzymes<br/><br/>1.03.6. Enzyme Applications<br/><br/>1.03.7. Conclusions<br/><br/>1.04. Immobilized Biocatalysts<br/><br/>1.04.1. Introduction: Definitions and Scope<br/><br/>1.04.2. Applications of Immobilized Enzymes<br/><br/>1.04.3. Methods of Enzyme Immobilization<br/><br/>1.04.4. Properties of Immobilized Enzymes<br/><br/>1.04.5. Evaluation of Enzyme Immobilization<br/><br/>1.04.6. Heterogeneous Biocatalysis<br/><br/>1.04.7. Future Prospects for Immobilized Biocatalysts<br/><br/>1.05. Lipids, Fatty Acids<br/><br/>Glossary<br/><br/>1.05.1. Introduction<br/><br/>1.05.2. Structure of Fatty Acids<br/><br/>1.05.3. Nomenclature<br/><br/>1.05.4. Form in the Cell<br/><br/>1.05.5. What Do Lipids Do?<br/><br/>1.05.6. Biosynthesis of Fatty Acids and Lipids<br/><br/>1.05.7. Biochemistry of Lipid Accumulation<br/><br/>1.06. DNA Cloning in Plasmid Vectors<br/><br/>Glossary<br/><br/>1.06.1. Introduction<br/><br/>1.06.2. Cloning Vectors: Replication Origins and Partition Regions<br/><br/>1.06.3. Cloning Vectors: Selection Markers<br/><br/>1.06.4. Preparing DNA Fragments for Ligation<br/><br/>1.06.5. Ligation Systems<br/><br/>1.06.6. Methods of Bacterial and Yeast Transformation<br/><br/>1.06.7. Exploitation of Bacteriophage Packaging for DNA Cloning in Plasmid Vectors<br/><br/>1.06.8. Screening of Plasmid Clones in Bacteria for the Desired Recombinant Plasmids<br/><br/>1.06.9. Vector-Implemented Systems for the Direct Selection of Recombinant Plasmids<br/><br/>1.06.10. Direct Selection of Recombinant Plasmids Involving Restriction Enzyme Digestion of the Ligation Mixture<br/><br/>1.06.11. Particular Features of Oligonucleotides’ Cloning<br/><br/>1.06.12. Particular Features of Cloning of PCR Amplicons<br/><br/>1.06.13. Introduction of Deletions into Plasmids<br/><br/>1.06.14. Instability of Recombinant Plasmids<br/><br/>1.06.15. DNA Cloning Using Site-Specific Recombination<br/><br/>1.06.16. DNA Cloning Using Homologous (General) Recombination<br/><br/>1.06.17. Employment of Transposons for In Vivo Cloning and Manipulation of Large Plasmids<br/><br/>1.06.18. Conclusion<br/><br/>1.07. Structure and Biosynthesis of Glycoprotein Carbohydrates<br/><br/>Glossary<br/><br/>Acknowledgments<br/><br/>1.07.1. Introduction<br/><br/>1.07.2. Monosaccharide Structure<br/><br/>1.07.3. Oligosaccharide Structure<br/><br/>1.07.4. Biosynthesis of Glycoproteins<br/><br/>1.07.5. Glycosylation of Therapeutic Glycoproteins<br/><br/>1.08. Nucleotide Metabolism<br/><br/>Glossary<br/><br/>1.08.1. Introduction<br/><br/>1.08.2. Synthesis of Phosphoribosyl Diphosphate (PRPP)<br/><br/>1.08.3. Purine Biosynthesis<br/><br/>1.08.4. Pyrimidine Biosynthesis<br/><br/>1.08.5. Nucleoside Triphosphate Formation<br/><br/>1.08.6. Deoxyribonucleotide Biosynthesis<br/><br/>1.08.7. Nucleotide Salvage<br/><br/>1.08.8. Purine and Pyrimidine Catabolism<br/><br/>1.08.9. Regulation of Gene Expression in Bacterial Nucleotide Synthesis<br/><br/>1.08.10. Exploitation of the Knowledge of Nucleotide Metabolism in Biotechnology<br/><br/>1.09. Organic Acids<br/><br/>Glossary<br/><br/>1.09.1. Introduction<br/><br/>1.09.2. Citric Acid<br/><br/>1.09.3. Gluconic Acid<br/><br/>1.09.4. Lactic Acid<br/><br/>1.09.5. Itaconic Acid<br/><br/>1.09.6. Other Acids<br/><br/>1.10. Peptides and Glycopeptides<br/><br/>Glossary<br/><br/>1.10.1. Introduction<br/><br/>1.10.2. Peptide Hormones<br/><br/>1.10.3. Neuropeptides<br/><br/>1.10.4. Antibacterial Peptides<br/><br/>1.10.5. Glycosylation Is a Common and Important Post-Translational Modification of Peptides<br/><br/>1.10.6. Common Glycosidic Linkages<br/><br/>1.10.7. Peptide Synthesis<br/><br/>1.10.8. Glycopeptide Synthesis<br/><br/>1.10.9. Peptides and Glycopeptides as Models of Proteins and Glycoproteins<br/><br/>1.10.10. Application of Synthetic Peptides and Glycopeptides for the Treatment of Disease<br/><br/>1.10.11. Summary<br/><br/>1.11. Protein Structural Analysis<br/><br/>Glossary<br/><br/>1.11.1. Introduction<br/><br/>1.11.2. Protein X-ray Crystallography<br/><br/>1.11.3. NMR Spectroscopy<br/><br/>1.11.4. Structure Analysis Using Intrinsic Protein Fluorescence<br/><br/>1.11.5. Conclusions<br/><br/>1.12. Secondary Metabolites<br/><br/>Glossary<br/><br/>1.12.1. Introduction<br/><br/>1.12.2. Antibiotics<br/><br/>1.12.3. Other Applications of Secondary Metabolites<br/><br/>1.13. Cell Line Isolation and Design<br/><br/>Glossary<br/><br/>1.13.1. Introduction<br/><br/>1.13.2. Clone Selection and Isolation<br/><br/>1.13.3. Automating Clone Screening<br/><br/>1.13.4. Designer Cell Lines for Bioproduction<br/><br/>1.13.5. Future Perspectives and Conclusions<br/><br/>1.14. Cell Preservation Technology<br/><br/>Glossary<br/><br/>1.14.1. Introduction<br/><br/>1.14.2. Hypothermic Storage<br/><br/>1.14.3. Hypothermic Continuum<br/><br/>1.14.4. Cryopreservation<br/><br/>1.14.5. Modes of Cell Death<br/><br/>1.14.6. Cell Death Continuum<br/><br/>1.14.7. Preservation-Induced Cell Death<br/><br/>1.14.8. Targeted Control of Molecular-Based Death<br/><br/>1.14.9. Concluding Thoughts<br/><br/>1.15. Cytoskeleton and Cell Motility<br/><br/>Glossary<br/><br/>1.15.1. Introduction<br/><br/>1.15.2. Myosins<br/><br/>1.15.3. Cell Migration<br/><br/>1.15.4. Involvement of Unconventional Myosins in Cell Migration and Trafficking<br/><br/>1.16. Design of Culture Media<br/><br/>Glossary<br/><br/>1.16.1. Introduction<br/><br/>1.16.2. Universal Requirements<br/><br/>1.16.3. Specific Requirements<br/><br/>1.16.4. Methods for Media Design<br/><br/>1.16.5. Manufacturing of the Designed Medium<br/><br/>1.16.6. Regulatory Considerations<br/><br/>1.16.7. Quality Control Testing<br/><br/>1.16.8. Security of Supply<br/><br/>1.16.9. Summary<br/><br/>1.17. Protein Folding in the Endoplasmic Reticulum<br/><br/>Glossary<br/><br/>Acknowledgments<br/><br/>1.17.1. Introduction: Protein Folding<br/><br/>1.17.2. The Endoplasmic Reticulum as a Folding, Assembly, and Trafficking Vehicle<br/><br/>1.17.3. Key Chaperones Assisting Folding in the ER<br/><br/>1.17.4. Calnexin and Calreticulin: Glycosylation and Glycoprotein Quality Control<br/><br/>1.17.5. PDI: Redox-Dependent Folding and Disulfide Bond Formation<br/><br/>1.17.6. Glycosylation Glycosylphosphatidylinositol Anchor Addition<br/><br/>1.17.7. Quality Control and ER-Associated Degradation<br/><br/>1.17.8. From the ER to the Golgi<br/><br/>1.17.9. Protein-Folding Status Is Communicated to the Cytosol and Nucleus via the UPR<br/><br/>1.17.10. Transduction of the ER Stress/UPR Signal by Three Proximal Sensors<br/><br/>1.17.11. UPR and Apoptosis<br/><br/>1.17.12. Protein Misfolding, ER Dyshomeostasis, and Human Diseases<br/><br/>1.17.13. Concluding Remarks<br/><br/>1.18. Extremophiles<br/><br/>Glossary<br/><br/>1.18.1. Introduction<br/><br/>1.18.2. The Diversity<br/><br/>1.18.3. High Temperature<br/><br/>1.18.4. Low Temperatures<br/><br/>1.18.5. Low pH<br/><br/>1.18.6. Alkaline pH<br/><br/>1.18.7. Conclusion<br/><br/>1.19. Metabolic Design and Control for Production in Prokaryotes<br/><br/>Glossary<br/><br/>1.19.1. Introduction<br/><br/>1.19.2. Classical Mutagenesis<br/><br/>1.19.3. Protoplast Fusion and Genome Shuffling<br/><br/>1.19.4. Recombinant DNA Technology and First-Generation Metabolic Engineering<br/><br/>1.19.5. Quantitative Approaches for Metabolic Design<br/><br/>1.19.6. Targeted Combinatorial Engineering<br/><br/>1.19.7. Synthetic Biology: Parts, Devices, and Circuits<br/><br/>1.20. Microbial Growth Dynamics<br/><br/>Glossary<br/><br/>1.20.1. Introduction<br/><br/>1.20.2. Kinetic Models of Microbial Growth<br/><br/>1.20.3. Growth Dynamic Variation as Dependent on Internal and External Factors<br/><br/>1.21. Modes of Culture/Animal Cells<br/><br/>Glossary<br/><br/>1.21.1. Introduction<br/><br/>1.21.2. Batch Culture: The Basis for All Cell Culture Systems<br/><br/>1.21.3. Fed-Batch Culture: Dominator of Industrial-Scale Processes<br/><br/>1.21.4. Perfusion Culture: The Most Sophisticated Process<br/><br/>1.21.5. Concluding Remarks on the Selection of Culture Mode<br/><br/>1.22. Modes of Culture/Microbial<br/><br/>Glossary<br/><br/>1.22.1. Introduction<br/><br/>1.22.2. Modes of Microbial Culture<br/><br/>1.22.3. When the Microbe Itself Is the End Product<br/><br/>1.22.4. Algal Biodiesel: A Case Study in Contemporary Challenges for Microbial Culture<br/><br/>1.22.5. Concluding Remarks<br/><br/>1.23. Photosynthesis and Photoautotrophy<br/><br/>Glossary<br/><br/>1.23.1. Introduction<br/><br/>1.23.2. Energy Absorption, Trapping, Conversion, and Storage<br/><br/>1.23.3. Photostasis and Cellular Energy Imbalance<br/><br/>1.23.4. Photoacclimation Tailors the Photosynthetic Apparatus<br/><br/>1.23.5. Acclimation to Low Temperature Mimics Photoacclimation<br/><br/>1.23.6. Conclusions<br/><br/>1.24. Protein Expression in Insect Cells<br/><br/>Glossary<br/><br/>1.24.1. Historical Background and General Introduction<br/><br/>1.24.2. Baculovirus Biology<br/><br/>1.24.3. The Origins of the BEVS<br/><br/>1.24.4. Baculovirus Recombination in Bacteria: the Development of Bacmids<br/><br/>1.24.5. Hybrid Systems: Bacmid Recombination in Insect Cells<br/><br/>1.24.6. Baculovirus Recombination In Vitro<br/><br/>1.24.7. Nonlytic Systems for Protein Expression in Insect Cells<br/><br/>1.24.8. Insect Cells<br/><br/>1.24.9. Insect Cell Culture<br/><br/>1.24.10. Removing Bottlenecks in the BEVS<br/><br/>1.24.11. Concluding Summary<br/><br/>1.25. Stem Cells<br/><br/>Glossary<br/><br/>1.25.1. Introduction<br/><br/>1.25.2. Human Embryonic Stem Cells<br/><br/>1.25.3. Human-Induced Pluripotent Stem Cells<br/><br/>1.25.4. Neural Stem Cells<br/><br/>1.25.5. Mesenchymal Stem Cells<br/><br/>1.25.6. Hematopoietic Stem Cells<br/><br/>1.26. Structural Organization of Cells – The Cytoskeleton<br/><br/>Glossary<br/><br/>Acknowledgments<br/><br/>1.26.1. Introduction<br/><br/>1.26.2. Molecular and Supramolecular Components<br/><br/>1.26.3. Cytoskeletal Arrays and Their Structural Functions<br/><br/>1.26.4. Motility<br/><br/>1.26.5. Diseases and the Cytoskeleton<br/><br/>1.27. Viruses Produced from Cells<br/><br/>Glossary<br/><br/>1.27.1. Introduction<br/><br/>1.27.2. Cell Culture<br/><br/>1.27.3. Types of Growth Flasks<br/><br/>1.27.4. Parameters of Virus Growth<br/><br/>1.27.5. Virus Purification<br/><br/>1.27.6. Future Perspectives<br/><br/>1.28. Cell Transfection<br/><br/>Glossary<br/><br/>1.28.1. Introduction<br/><br/>1.28.2. Methods of Transfection<br/><br/>1.28.3. Advances in Large-Scale Transfection Technology<br/><br/>1.29. mRNA Translation and Recombinant Gene Expression from Mammalian Cell Expression Systems<br/><br/>1.29.1. Introduction<br/><br/>1.29.2. Translational Machinery<br/><br/>1.29.3. Manipulation of mRNA for Optimal Translational Efficiency<br/><br/>1.29.4. Importance of 5′-UTR and Secondary Structure in 5′-UTR Region of mRNA<br/><br/>1.29.5. mRNA Translation Shutdown<br/><br/>1.29.6. MicroRNAs and Translational Control<br/><br/>1.29.7. In Vitro mRNA Translation Systems<br/><br/>1.29.8. Conclusions and Future Prospects<br/><br/>1.30. Posttranslation Modifications Other Than Glycosylation<br/><br/>Glossary<br/><br/>Acknowledgments<br/><br/>1.30.1. Introduction<br/><br/>1.30.2. Cell Influences on Protein Expression<br/><br/>1.30.3. Induction of Protein Expression<br/><br/>1.30.4. Improving the Protein Folding and Secretory Pathways<br/><br/>1.30.5. Role of Chaperones<br/><br/>1.30.6. Multiple Gene Activators<br/><br/>1.30.7. Cell Clearance of Misfolded Proteins<br/><br/>1.30.8. Protein Aggregation<br/><br/>1.30.9. Analytical Techniques for Protein Aggregate Detection<br/><br/>1.30.10. Asparagine Deamidation<br/><br/>1.30.11. Methionine Oxidation<br/><br/>1.30.12. Surface-Plasmon Resonance<br/><br/>1.30.13. Conclusions<br/><br/>1.31. Engineering Protein Folding and Secretion in Eukaryotic Cell Factories<br/><br/>Glossary<br/><br/>1.31.1. Introduction<br/><br/>1.31.2. Direct Engineering of Recombinant Protein Folding and Assembly<br/><br/>1.31.3. Engineering the Regulation of Protein Folding and Assembly: The Unfolded Protein Response<br/><br/>1.31.4. Glycosylation Engineering for Improved Protein Processing<br/><br/>1.31.5. Engineering of the Secretory Apparatus<br/><br/>1.31.6. Mathematical Modeling of Recombinant Protein Synthesis and Secretion<br/><br/>1.32. Glycomics<br/><br/>Glossary<br/><br/>1.32.1. Introduction<br/><br/>1.32.2. Methods for the Structural Analysis of Glycans<br/><br/>1.32.3. Glycomics in Bioproduction<br/><br/>1.32.4. The Changing Landscape of Regulatory Agencies toward Glycosylation of Biopharmaceuticals<br/><br/>1.32.5. Summary<br/><br/>1.33. Metabolomics – The Combination of Analytical Biochemistry, Biology, and Informatics<br/><br/>Glossary<br/><br/>Acknowledgments<br/><br/>1.33.1. Introduction<br/><br/>1.33.2. Technologies Used to Measure Metabolites<br/><br/>1.33.3. Metabolomics Approaches<br/><br/>1.33.4. Bioinformatics: What Can It Do<br/><br/>1.33.5. What Does the Informatician Need to Analyze the High-Density Data?<br/><br/>1.33.6. Data Preprocessing: From Raw to Sense<br/><br/>1.33.7. Requirements and Problems of Statistical and Multivariant Analysis of Metabolomics Data<br/><br/>1.33.8. Conclusions<br/><br/>1.34. Theory and Applications of Proteomics<br/><br/>Glossary<br/><br/>1.34.1. Introduction<br/><br/>1.34.2. Proteomics Technologies<br/><br/>1.34.3. Separation Technologies<br/><br/>1.34.4. Quantitative Proteomics<br/><br/>1.34.5. Data Processing<br/><br/>1.34.6. Applications in Biotechnology<br/><br/>1.35. Systems Metabolic Engineering for the Production of Non-innate Chemical Compounds<br/><br/>Glossary<br/><br/>1.35.1. Introduction and Scope<br/><br/>1.35.2. Systems Metabolic Engineering<br/><br/>1.35.3. Summary<br/><br/>1.36. Apoptosis<br/><br/>Glossary<br/><br/>1.36.1. Introduction<br/><br/>1.36.2. Apoptosis Regulators and Executioners<br/><br/>1.36.3. Apoptotic Pathways<br/><br/>1.36.4. Apoptosis and Autophagy<br/><br/>1.36.5. Inhibition of Apoptosis<br/><br/>1.36.6. Apoptosis affects Metabolic Pathways<br/><br/>1.36.7. Conclusion<br/><br/>1.37. Design Principles of Self-assembling Peptides and Their Potential Applications<br/><br/>Glossary<br/><br/>1.37.1. Introduction<br/><br/>1.37.2. Design Principles of Self-Assembling Peptides<br/><br/>1.37.3. Applications of Self-Assembling Peptides<br/><br/>1.38. Rational Design of Strategies Based on Metabolic Control Analysis<br/><br/>Glossary<br/><br/>Acknowledgments<br/><br/>1.38.1. Introduction<br/><br/>1.38.2. Fundamentals of Metabolic Control Analysis<br/><br/>1.38.3. Modulation of Clinically and Biotechnologically Relevant Metabolism<br/><br/>1.38.4. Concluding Remarks<br/><br/>1.39. Unfolded Protein Response<br/><br/>Glossary<br/><br/>Acknowledgments<br/><br/>1.39.1. Introduction<br/><br/>1.39.2. Molecular Mechanism of the UPR<br/><br/>1.39.3. Stress Responses in Other Organelles<br/><br/>1.39.4. Concluding Remarks<br/><br/>1.40. Cell Migration<br/><br/>Glossary<br/><br/>Acknowledgments<br/><br/>1.40.1. Introduction<br/><br/>1.40.2. Biological Mechanisms for Cell Migration<br/><br/>1.40.3. Cell Migration in Selected Physiological Systems<br/><br/>1.40.4. Approaches for Measuring Cell Migration<br/><br/>1.40.5. Summary and Outlook<br/><br/>1.41. Biofilms<br/><br/>Glossary<br/><br/>1.41.1. Introduction<br/><br/>1.41.2. Model Systems for Growing and Analyzing Biofilms<br/><br/>1.41.3. Heterogeneity in Biofilms<br/><br/>1.41.4. Stages of Biofilm Development<br/><br/>1.41.5. Regulation of Biofilm Development<br/><br/>1.41.6. Biofilm Infections<br/><br/>1.41.7. Pathogenicity and Antibiotic Resistance of Biofilms<br/><br/>1.41.8. Antibiotics Act as Signals that Stimulate Biofilm Formation<br/><br/>1.41.9. Concluding Remarks<br/><br/>1.42. Flow Cytometry<br/><br/>Glossary<br/><br/>1.42.1. Introduction<br/><br/>1.42.2. Principles and Instrumentation<br/><br/>1.42.3. Data Representation<br/><br/>1.42.4. Common Applications<br/><br/>1.43. Biological Imaging by Superresolution Light Microscopy<br/><br/>Glossary<br/><br/>Acknowledgments<br/><br/>1.43.1. Introduction<br/><br/>1.43.2. The Case for Superresolution Microscopy Techniques<br/><br/>1.43.3. Near-Field Scanning Optical Microscopy<br/><br/>1.43.4. Stimulated Emission Depletion<br/><br/>1.43.5. Superresolution Structured Illumination Microscopy<br/><br/>1.43.6. Photoactivation Localization Microscopy, Fluorescence Photoactivation Localization Microscopy, and Stochastic Optical Reconstruction Microscopy<br/><br/>1.43.7. Conclusions<br/><br/>1.44. Cell Isolation from Tissue<br/><br/>Glossary<br/><br/>1.44.1. Introduction<br/><br/>1.44.2. Tissue/Organ Procurement<br/><br/>1.44.3. Tissue/Organ Preservation<br/><br/>1.44.4. Tissue/Organ Rinsing<br/><br/>1.44.5. Tissue/Organ Fragmentation<br/><br/>1.44.6. Cell Dissociation<br/><br/>1.44.7. Purification<br/><br/>1.44.8. Cell Yield, Viability, and Purity Assessment<br/><br/>1.44.9. Conclusions<br/><br/>1.45. Nanobiotechnology<br/><br/>1.45.1. Introduction<br/><br/>1.45.2. Nanoparticles<br/><br/>1.45.3. Role of Nanobiotechnology in Molecular Diagnostics<br/><br/>1.45.4. Pharmaceutical Applications of Nanobiotechnology<br/><br/>1.45.5. Role of Nanobiotechnology in Biological Therapies<br/><br/>1.45.6. Clinical Nanomedicine<br/><br/>1.45.7. Nanooncology<br/><br/>1.45.8. Nanoneurology<br/><br/>1.45.9. Nanocardiology<br/><br/>1.45.10. Nanosurgery<br/><br/>1.45.11. Nanorobotics<br/><br/>1.45.12. Role of Nanobiotechnology for the Development of Personalized Medicine<br/><br/>1.45.13. Safety Issues of Nanoparticles<br/><br/>1.45.14. Future Prospects of Nanobiotechnology<br/><br/>1.46. Effects of Shear Stress on Cells<br/><br/>Glossary<br/><br/>1.46.1. Introduction<br/><br/>1.46.2. Shear Stress<br/><br/>1.46.3. Mechanisms of Mechanosignaling<br/><br/>1.46.4. Role of Shear Stress on ECs<br/><br/>1.46.5. Shear Stress Plays a Role in Stem Cell Fate<br/><br/>1.47. Viruses and Virus-Like Particles in Biotechnology<br/><br/>Glossary<br/><br/>Acknowledgments<br/><br/>1.47.1. Introduction<br/><br/>1.47.2. Types of Viruses<br/><br/>1.47.3. Types of VLPs<br/><br/>1.47.4. Production Platforms: A Focus on Animal Cell Technology<br/><br/>1.47.5. Applications: Prevention and Treatment<br/><br/>1.47.6. Bioengineering Challenges<br/><br/>1.47.7. Concluding Remarks and Future Trends<br/><br/>1.48. Mathematical Models in Biotechnology<br/><br/>Glossary<br/><br/>1.48.1. Introduction<br/><br/>1.48.2. Metabolic Network Models and Flux Balance Analysis<br/><br/>1.48.3. Reverse Engineering of Gene Regulatory Networks<br/><br/>1.48.4. Continuous Ordinary Differential Equation-Based Dynamic Models<br/><br/>1.48.5. Single-Cell Models and Stochastic Simulations<br/><br/>1.48.6. Qualitative Models: Fuzzy Logic and Petri Nets<br/><br/>1.48.7. Conclusion<br/><br/>1.49. Immunoassays in Biotechnology<br/><br/>Glosssary<br/><br/>Acknowledgments<br/><br/>1.49.1. Introduction<br/><br/>1.49.2. Immunoassay Formats<br/><br/>1.49.3. Applications<br/><br/>1.49.4. Conclusions<br/><br/>1.50. Mass Spectrometry<br/><br/>Glossary<br/><br/>Acknowledgments<br/><br/>1.50.1. Introduction<br/><br/>1.50.2. Recent Ionization Techniques<br/><br/>1.50.3. Commonly Used Mass (m/z) Analyzers<br/><br/>1.50.4. Online and Offline Coupling of MS with Liquid Chromatography and Electrophoresis<br/><br/>1.50.5. Quantitative Analysis (i-tag, i-traq, etc.)<br/><br/>1.50.6. Concluding Remarks<br/><br/>1.51. Bioprocessing Techniques<br/><br/>Glossary<br/><br/>1.51.1. Introduction<br/><br/>1.51.2. Production Strain Development<br/><br/>1.51.3. Fermentation Process<br/><br/>1.51.4. Product Recovery and Purification<br/><br/>1.51.5. Process Validation<br/><br/>1.51.6. Process Documentation<br/><br/>1.51.7. Conclusion |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Reference Books |
| Withdrawn status | Lost status | Damaged status | Not for loan | Collection Type | Home library | Current library | Shelving location | Date acquired | Full call number | Accession number | Date last seen | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Not For Loan | Reference Collection | Central Library, Sikkim University | Central Library, Sikkim University | Reference | 29/08/2016 | 660.6 MOO/C | P35149 | 23/09/2022 | Reference Books |