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Walsh, Christopher.

Antibiotics: aqctions, origins, resistance/ Christopher Walsh - Washington: ASM Press, 2003. - x, 335 p. : ill. ; 26 cm.

1 Antibiotics : initial concepts

2 Introduction to major antibiotic classes and modes of action

3 Antibiotics that act on cell wall biosynthesis

4 Antibiotics that block bacterial protein biosynthesis

5 Antibiotics that block DNA replication and repair : the Quinolones

6 Other targets of antibacterial drugs

7 Natural and producer immunity versus acquired resistance

8 Enzymatic destruction or modification of the antibiotic by resistant bacteria

9 Antibiotic resistance by efflux pumps

10 Antibiotic resistance by replacement or modification of the antibiotic target

11 Regulation of antibiotic biosynthesis in producer organisms

12 Polyketide antibiotic biosynthesis : assembly line enzymology

13 Enzymatic assembly lines for nonribosomal peptide antibiotics

14 Biosynthesis of other classes of antibiotics

15 New looks at targets

16 New molecules

17 Contexts and challenges for the use of new antibiotics.

ISBN: 1555818935

Subjects--Topical Terms:
Antibiotics
Drug resistance in microorganisms

Dewey Class. No.: 615.329 / CHR/A